Potential implications of the use of Rapanea melanophloeos (L.) Mez against mycobacteria

Investigating Mtr and MshC as potential targets in the fight against Mycobacterium abscessus infections

“…MSH and the MSHdependent enzymes are highly specific components as they are only found in Actinomycetes (248). The human-analog of MSH, GSH, is a protein with a similar function but which is not found in mycobacteria (249,250). Although MSH and GSH exert a similar function, they possess certain differences; while GSH is a tripeptide of gamma-glutamyl-cysteinylglycine, MSH is a cysteinyl pseudodisaccharide (101,102).…”