Potential Interactions Between Complementary/Alternative Products and Conventional Medicines in a Medicare Population

Elmer, Gary W.; Lafferty, William E.; Tyree, Patrick T.; Lind, Bonnie K.

doi:10.1345/aph.1k221

Cited by 80 publications

(71 citation statements)

References 27 publications

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“…28,29 Use of CAM is reportedly increasing among elderly persons, including concomitant use of herbal supplements with conventional medications. 30 Adverse reactions due to polypharmacy, increased sensitivity to some medications, and decreased organ function for medication processing and clearance may be of greater concern to the elderly than to younger persons. Compared with younger and stronger patients, older and frailer patients admitted to the intensive care unit experience higher rates of mortality and morbidity, affecting quality of life and placing a greater burden on resources.…”

Section: Implications For Acute and Critical Care Nursesmentioning

confidence: 99%

Introduction to Complementary, Alternative, and Traditional Therapies

Kramlich

2014

Critical Care Nurse

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The use of complementary, alternative, and traditional therapies is increasing in the United States, and patients and their families are bringing these practices into the acute care setting. Acute and critical care nurses are in a unique and trusted position to advocate for their patients and to promote safe incorporation of complementary, alternative, and traditional therapies into the plan of care.

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Section: Implications For Acute and Critical Care Nursesmentioning

confidence: 99%

Introduction to Complementary, Alternative, and Traditional Therapies

Kramlich

2014

Critical Care Nurse

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“…Although there is a general belief that CAM remedies are safer than conventional ones, adverse events have been reported for several CAM therapies [8,10]. Furthermore, traditional medicines containing toxic heavy metals or undeclared prescription drugs have been described [9], and several interactions between CAM and conventional remedies have been reported [6,16]. Case series concerning liver problems following the repeated use of Chinese herbal medicines for skin disorders, allergic reactions to royal jelly and propolis, as well as heavy metal poisoning caused by remedies from the Indian subcontinent have been described [20].…”

Section: Introductionmentioning

confidence: 99%

Accidental intakes of remedies from complementary and alternative medicine in children—analysis of data from the Swiss Toxicological Information Centre

Zuzak

Rauber-Lüthy²,

Simões-Wüst³

2009

Eur J Pediatr

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The use of complementary and alternative medicine (CAM) in Switzerland is rather high, and therefore, the occurrence of accidental intakes of CAM remedies by children and associated intoxications is to be expected. In the present study, the inquiries to the Swiss Toxicological Information Centre that took place from 1998 until 2007 and concerned accidental, unintended intakes of CAM remedies by children were analysed. Inquiries for information were performed by concerned care-givers, physicians, pharmacists and others in case of acute accidental intake of CAM remedies. Feedbacks from physicians about paediatric patients with acute intoxication possibly associated with the accidental ingestion of CAM remedies were as well considered. During the study period, 3,158 accidental intakes of CAM remedies (1,015 of herbal and 2,143 of homeopathic remedies) were reported, corresponding to 8.6% of all reported accidental intakes of pharmaceutical products by children. No significant increase of the yearly number of accidental intakes of CAM remedies was detected during the study period. There was no accidental intake of CAM remedies leading to severe signs or symptoms. Concerning the herbal remedies, three intoxications of moderate and 28 of minor severity were reported. Nine children with intoxication from homeopathic remedies were reported, with minor symptoms only. All other accidental intakes of CAM remedies did not lead to intoxications and evolved without manifestations. The data show that accidental, unintended intake of CAM remedies happened in children, but developed mostly harmlessly. Comparing herbal with homeopathic remedies, accidental intakes with homeopathic remedies were more common, but intoxications associated with manifestations were observed more frequently with herbal remedies.

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“…The safety concerns raised by the co-use of herbal products and conventional medicines is absolutely non-negligible (Canter and Ernst 2004;Elmer et al 2007). A systematic review summarized clinical pharmacokinetic studies on the interactions between herbs and index medicines (Mills et al 2005).…”

Section: Introductionmentioning

confidence: 99%

Effects of St. John's wort extract on indinavir pharmacokinetics in rats: Differentiation of intestinal and hepatic impacts

Ho¹,

Huang²,

Hsueh³

et al. 2009

Life Sciences

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Potential Interactions Between Complementary/Alternative Products and Conventional Medicines in a Medicare Population

Abstract: Background-Despite the high prevalence of Complementary and Alternative Medicine (CAM) product use among the elderly, little is known about the extent of concurrent CAM-conventional medicine use and the potential for adverse reactions.

Cited by 80 publications

References 27 publications

Introduction to Complementary, Alternative, and Traditional Therapies

Introduction to Complementary, Alternative, and Traditional Therapies

Accidental intakes of remedies from complementary and alternative medicine in children—analysis of data from the Swiss Toxicological Information Centre

Effects of St. John's wort extract on indinavir pharmacokinetics in rats: Differentiation of intestinal and hepatic impacts

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