Potential Introduction of Cell Technologies to Improve Dental Implant Surface Preparing

Kupryakhin, Sergey; Лепилин, А. В.; Kupryakhin, Vyacheslav; Postnikov, M.S.; Domenyuk, Dmitry

doi:10.35630/2199-885x/2019/9/2/122

Cited by 10 publications

(6 citation statements)

References 17 publications

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“…The bone tissue quality is one of the essential factors ensuring the success of implantological treatment, as well it is a reflection of the metabolic processes underway [19][20][21]. Medicine nowadays views histological and histomorphometric studies as the gold standard for evaluating the bone tissue microarchitectonics, the said types of examination allowing accurate assessment of the bone structural features and qualitative parameters, identifying the scale of the existing changes, and determining the effectiveness of the respective treatment and its effect on the mechanisms remodeling [22][23][24].…”

Section: Introductionmentioning

confidence: 99%

Jaw Bones Microarchitectonics and Morphology in Patients With Diabetes Mellitus

Domenyuk¹,

Kochkonyan²,

Konnov³

et al. 2022

ArveMED

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The study, while aiming to study the microarchitectonics and morphology of the mandible alveolar part at dentition defects in 24 males (aged – 50-65; with type 2 diabetes mellitus going through the compensation stage following the correction of bone remodeling imbalance), and 19 healthy persons belonging to the same age group, implied analyzing 3D cross-sections of the adentia zone (through cone-beam computed tomograms), along with bone tissue biopsy histological examination, obtained from the projection area of dental implants. All patients had their biochemical features of bone metabolism within the reference values, the volume of the bone tissue at the missing teeth area was classified as Category A and B (by C.E. Mich, K.B.M. Judy, 1987), while the densitometry value at the lumbar spine and femoral neck (based on T-criterion) fell within the normal value (> -1SD). The X-ray and histological studies carried out in the studied groups, identified no significant differences in the quantitative and qualitative parameters of the mandibular alveolar part within the area of missing teeth. The morphology of the lower jaws alveolar part at the adentia area in healthy patients, which was represented by strongly interconnected trabeculae, single elements of adipose tissue in peritrabecular spaces, small resorption lacunae on the beam surface, few bonding lines, a depleted pool of osteogenic cells observed in the endossal layer – all these point at an age-related decrease in the intensity of reparation processes, as well as at a decreasing rate of bone tissue remodeling and development. The histological specifics of the mandibular alveolar part at the dentition defects in patients with type 2 diabetes, after pharmacological correction of the bone remodeling imbalance by way of interconnected trabeculae, local elements of adipose tissue against red bone marrow, a significant number of activated osteoblasts and inactive flattened osteogenic cell elements, enhanced activity of osteoblastic differon cells, as well as zones of the developing weakly mineralized osteoid, serve proof to an increase in the intensity of bone tissue metabolic processes, the predominance of the bone development phase over resorption and active osteogenesis. The results of X-ray and morphological studies show that in order to bring bone remodeling back to normal and reduce the risk of postoperative complications at the dental implantation in patients with compensated type 2 diabetes prior to dental rehabilitation, a good choice would imply carrying out pathogenetic pharmacological correction using groups of drugs capable of reducing bone resorption and enhancing bone development.

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Section: Introductionmentioning

confidence: 99%

Jaw Bones Microarchitectonics and Morphology in Patients With Diabetes Mellitus

Domenyuk¹,

Kochkonyan²,

Konnov³

et al. 2022

ArveMED

View full text Add to dashboard Cite

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“…However, failure to follow oral hygiene requirements and periodontitis belong to the risk factors for peri-implantitis [8][9][10][11]13]. The hypothesis here is that pathogenic microorganisms detected on periodontal teeth can develop colonies, so implants, similarly to cross-infection, develop a complication known as dental peri-implantitis.…”

Section: Introductionmentioning

confidence: 99%

Oral Homeostasisstatusin Mild Chronic Generalized Periodontitis and Mild Dental Peri-Implantitis

Tlustenko¹,

Tlustenko²,

Gusyakova³

et al. 2021

AREM

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The paper is focused on evaluating the oral cavity homeostasis in patients with mild chronic generalized periodontitis (CGP) (Group 1, 35 persons) and mild peri-implantitis (Group 2, 30 persons). The control group included healthy individuals (20 persons) with neither dental nor somatic issues. The material used for the study was oral fluid. The general metabolic processes in the periodontal and peri-implant area tissues were described based on analysis of the protein and mineral metabolism indicators, as well as on the hygiene and periodontal status indices. The paper presents the results of a comparative assessment involving Groups I and II with the control group and between Groups I and II. Our findings show changes in ion balance in both groups. Significant disturbances in the protein and mineral metabolism have been identified in the main groups, which contributes to the development of inflammation and reduced detoxification in periodontal and peri-implant tissues. A rise in Calcium and Magnesium indicates destructive processes in bone tissues. In case of mild CGP, these changes are more prominent. The oral hygiene and periodontal status indices in Group I proved to be significantly worse. Therefore, while performing implantation on the background of chronic generalized periodontitis, it is important to take into account its metabolic imbalance and implement preventive measures

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“…Indications for the methods are expanding steadily. Certain pathological conditions affecting the patient's dental status may remain hidden and require a more detailed examination [12][13][14][15][16].…”

Section: Introductionmentioning

confidence: 99%

Orthopedic Treatment for Masticatory Muscles Parafunction: Explanation Based on Clinical and Functional Study

Tlustenko¹,

Tlustenko²

2020

AREM

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This study was conducted to investigate two clinical types of masticatory muscles parafunction: teeth compression and teeth grinding using clinical and functional methods. Teeth compression and teeth grinding were found to have a common tooth compression symptom. Our finding has been proven not only through clinical, yet via electromyographic and axiographic research methods as well. Based on the obtained data we developed a palatal plate-occlusal guard. It enables to fix reliably the lower jaw and reduces muscle tension. The proposed appliance helps prevent possible complications that occur in the course of orthopedic treatment.

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Potential Introduction of Cell Technologies to Improve Dental Implant Surface Preparing

Cited by 10 publications

References 17 publications

Jaw Bones Microarchitectonics and Morphology in Patients With Diabetes Mellitus

Jaw Bones Microarchitectonics and Morphology in Patients With Diabetes Mellitus

Oral Homeostasisstatusin Mild Chronic Generalized Periodontitis and Mild Dental Peri-Implantitis

Orthopedic Treatment for Masticatory Muscles Parafunction: Explanation Based on Clinical and Functional Study

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