Potential of Cameroonian Plants and Derived Products against Microbial Infections: A Review

Kuete, Victor

doi:10.1055/s-0030-1250027

Cited by 562 publications

(454 citation statements)

References 102 publications

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“…Another study showed that the MIC of the aqueous extract of P. dodecandra was 1% [6] . The MIC for novel pharmacological compounds should be <0.1% [17] . As the MIC of the aqueous extract of P. dodecandra against HCF was greater than the recommended level (0.1%), this extract could be considered inactive.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of berries of Phytolacca dodecandra for growth inhibition of Histoplasma capsulatum var. farciminosum and treatment of cases of epizootic lymphangitis in Ethiopia

Mekonnen

Makonnen²,

Aklilu³

et al. 2012

Asian Pacific Journal of Tropical Biomedicine

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Section: Discussionmentioning

confidence: 99%

Evaluation of berries of Phytolacca dodecandra for growth inhibition of Histoplasma capsulatum var. farciminosum and treatment of cases of epizootic lymphangitis in Ethiopia

Mekonnen

Makonnen²,

Aklilu³

et al. 2012

Asian Pacific Journal of Tropical Biomedicine

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“…59 The results are shown in Table 2. From the results, it was observed that compounds 2b, 2c and 2f showed good to moderate activity 63 for both standard and clinical strains of S. aureus; the amino alcohol 2o was Scheme 1. Synthesis of cardanol epoxide 1. active only against the standard strain.…”

Section: Resultsmentioning

confidence: 99%

Synthesis, Antibacterial and Antitubercular Evaluation of Cardanol and Glycerol‑Based β-Amino Alcohol Derivatives

Manda

Prasad

Thatikonda

et al. 2017

J. Braz. Chem. Soc.

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The synthesis of novel amino alcohol derivatives based on cardanol and glycerol were achieved in good yields and characterized by 1 H and 13 C NMR (nuclear magnetic resonance) and MS (mass spectrometry). In addition, we evaluated the in vitro antimicrobial activity against Gram-positive (Staphylococcus aureus, standard and clinical strains), Gram-negative (Escherichia coli) and M. tuberculosis bacterial strains. The bioassay results indicated that four compounds showed activity against S. aureus, including the clinical resistant strain, with MIC (minimum inhibitory concentration) ranging from 3.90 to 15.60 µg mL -1 and M. tuberculosis, with MIC 90 (minimum inhibitory concentration required to inhibit the growth of 90% of organisms) ranging from 3.18 to 7.36 µg mL -1 .Keywords: CNSL, cardanol, amino alcohols, epoxide ring opening, antimicrobial activity IntroductionThe synthesis of fine chemicals from natural renewable resources has received great interest in synthetic community and is becoming a significant and challenging theme for researchers of both the academic and industrial sectors. Among the renewable materials, cardanol has attracted considerable attention due to its unique nature.1 Cardanol is a low cost, naturally occurring renewable non-isoprenoic phenolic lipid-mixture of cashew nut shell liquid (CNSL). The structural benefits of cardanol are carrying reactive phenolic group and hydrophobic alkyl/alkenyl side chain at meta-position of phenolic group. With these unique structural features, cardanol and its derivatives are renowned amphiphilic building blocks and precursors of high-value fine chemicals and supramolecular structures. Its derivatives present many biological activities such as: fungicidal, bactericidal, molluscicidal, larvicidal, anti-inflammatory, antioxidant and, towards serious disorders like cancer and obesity. [2][3][4][5][6][7][8][9] It is also described in the literature in recent years, that cardanol frameworks are involved to build phenolic resins, 10-12 bio-based polymers, 13 epoxy curing resins, 14-16 reactive diluents, 17,18 and fluorescent compounds. 19,20 Similarly, glycerol is another important renewable material used in the synthesis of higher value-added fine chemicals through green chemistry procedures in the last years. It may be applied, for instance, to generate hydrogen gas, 21 Synthesis, Antibacterial and Antitubercular Evaluation of Cardanol and Glycerol-Based β-Amino Alcohol Derivatives J. Braz. Chem. Soc. 640 Cardanol and glycerol can be starting materials to prepare β-amino alcohols which is a vital interesting class of organic intermediates due to their abundant existence in nature and they are useful in the preparation of wide range of biologically active natural and synthetic frameworks, pharmaceuticals (e.g. β-blockers), unnatural β-amino acids, pesticides and chiral auxiliaries. [29][30][31][32] Additionally, β-amino alcohols have many applications as antibiotics, anti-bacterial drugs and, steroids.33 One of the most classical approaches toward the syn...

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“…In previous study, plants extract were considered active against M. tuberculosis if MIC was <100µg/mL (Borges-Argáez et al, 2007;Gautam et al, 2007;Okunade et al, 2004), <200µg/mL (Camacho-Corona et al, 2008;Tosun et al, 2004), < 1600µg/mL (Mohamad et al, 2011), ≤ 2048 µg/ml (Tekwu et al, 2012). In other paper, the antimicrobial activity of plant extracts was classified as significant (MIC ≤100µg/mL), moderate (100 < MIC < 625µg/mL), or weak (MIC > 625 µg/mL) (Kuete, 2010). Because of ethanolic extract of Brotowali exhibited antituberculosis activity against M. tuberculosis H37Rv with MIC 12.5mg/mL, so we interpreted that this activity was weak.…”

Section: Resultsmentioning

confidence: 99%

Antituberculosis Activity of Brotowali (Tinospora crispa) Extract and Fractions against Mycobacterium tuberculosis using Microplate Alamar Blue Assay Method

et al. 2017

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Tuberculosis (TB), in which caused by pathogenic bacteria, Mycobacterium tuberculosis, has become the major causes of death among all of infectious diseases. The increasing incidence of multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB ABSTRAK Tuberkulosis (TB) adalah penyakit yang disebabkan oleh infeksi Mycobacterium tuberculosis dan menjadi penyakit infeksi yang menyebabkan paling banyak kematian di dunia. Daruratnya penyakit TB dan meningkatnya kasus multidrug-resistant tuberculosis (MDR-TB) dan XDR-TB ini mendorong dilakukannya

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Potential of Cameroonian Plants and Derived Products against Microbial Infections: A Review

Cited by 562 publications

References 102 publications

Evaluation of berries of Phytolacca dodecandra for growth inhibition of Histoplasma capsulatum var. farciminosum and treatment of cases of epizootic lymphangitis in Ethiopia

Evaluation of berries of Phytolacca dodecandra for growth inhibition of Histoplasma capsulatum var. farciminosum and treatment of cases of epizootic lymphangitis in Ethiopia

Synthesis, Antibacterial and Antitubercular Evaluation of Cardanol and Glycerol‑Based β-Amino Alcohol Derivatives

Antituberculosis Activity of Brotowali (Tinospora crispa) Extract and Fractions against Mycobacterium tuberculosis using Microplate Alamar Blue Assay Method

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