2022
DOI: 10.1007/s11064-022-03809-4
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Potential of Capric Acid in Neurological Disorders: An Overview

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Cited by 9 publications
(3 citation statements)
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“…Capric acid has several targets including PPAR-γ, AMPA receptors, gut dysbiosis and inflammatory of oxidative stress pathways. Moreover, Capric acid exhibits an ameliorative effect of neurological diseases including affective disorders, epilepsy and Alzheimer's disease [53]. Resveratrol shows anti-aging, anticancer and antioxidant properties [54].…”
Section: Othersmentioning
confidence: 99%
“…Capric acid has several targets including PPAR-γ, AMPA receptors, gut dysbiosis and inflammatory of oxidative stress pathways. Moreover, Capric acid exhibits an ameliorative effect of neurological diseases including affective disorders, epilepsy and Alzheimer's disease [53]. Resveratrol shows anti-aging, anticancer and antioxidant properties [54].…”
Section: Othersmentioning
confidence: 99%
“…Capric acid, also known as decanoid acid, binds to the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor, a glutamate receptor that mediates synaptic transmission in the brain. Capric acid has antioxidative effects in neuronal cells 38 and has been implicated in the amelioration of several neurological diseases 39 so that further studies of the potential role of decreased capric acid levels for the development of DSPN appear promising. Adrenic acid-derived epoxy fatty acids have anti-nociceptive properties and can reduce inflammatory pain 40 so that a link between lower levels and higher risk of DSPN appears biologically plausible.…”
Section: Discussionmentioning
confidence: 99%
“…Lauric acid also imparted apoptosis in endometrial and breast cancer cells [46]. Thakur and colleagues recently reviewed the potential effects of DA on neurological disorders [47]. DA was reported to curb the expression of inflammatory and metastasis markers in colon cancer cells [28].…”
Section: Discussionmentioning
confidence: 99%