Potential of photoplethysmogram for the detection of calcification and stenosis in lower limb

Nirala, Neelamshobha; Periyasamy, R.; Kumar, Awanish

doi:10.1504/ijbra.2018.092704

Cited by 1 publication

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Heart rate exerts an important influence and must be considered. Our overall results do highlight the potential of the multi-site PPG technique as a tool to quickly assess patients for possible accelerated vascular changes over time, for example in diabetic and renal patients who are increased risk of blood vessel calcification (Nirala et al 2018). Future studies of multisite photoplethysmography could also investigate age-related changes in pulse timing measures and aim to compare these measurements with intimal thickening in the peripheral arteries.…”

Section: Discussionmentioning

confidence: 73%

“…Researchers have considered that risetime relates to arterial stiffness, i.e. compliance (Akl et al 2014, Lui et al 2015, Nirala et al 2018 and to peripheral resistance with vasodilatation and vasoconstriction changes Murray 1999, Kyle et al 2017), and also to potential presence of arterial occlusive disease (Sherebrin and Sherebrin 1990, Allen et al 2005and also, 2008, Allen and Hedley 2019, Peltokangas et al 2019. Pulse risetime and dynamics therein have also found other relevance with researchers studying sleep (Chua et al 2007), blood pressure estimation with machine learning methods (Khalid et al 2018), ageing by using a second derivative or 'acceleration' PPG (Takada et al 1996, Elgendi 2012, wearable sensors applications (Castaneda et al 2018), and also the study of vasospastic disease (Cooke et al 1985, Mckay et al 2014.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Age-related changes in pulse risetime measured by multi-site photoplethysmography

et al. 2020

View full text Add to dashboard Cite

Objective: It is accepted that changes in the peripheral pulse waveform characteristics occur with ageing. Pulse risetime is one important feature which has clinical value. However, it is unclear how it varies across the full age spectrum from child to senior and for different peripheral measurement sites. The objectives of this study were to determine the association between age and pulse risetime characteristics over an 8-decade age range at the ears, fingers, and toes, and to consider effects arising from differences in systolic blood pressure (SBP), height and heart rate. Approach: Multi-site photoplethysmography (MPPG) pulse waveforms were recorded non-invasively from the right and left ears, fingers, and toes of 304 normal healthy human subjects (range 6–87 years; 156 male and 148 female). SBP, height, and heart rate were also measured. Multi-site PPG pulse risetimes, and their site differences, were determined. Main results: Univariate regression analysis showed positive correlations with risetime for age (ears, fingers and toes: + 0.8, + 1.9, and + 1.1 ms/year, respectively), SBP (+0.5, + 1.3, and + 0.9 ms/mmHg) and height (+0.5, + 1.2, and + 1.0 ms/cm), but with a clear inverse association with heart rate (−1.8, − 2.5, and − 1.6 ms min) (P < 0.0001). No significant differences between male and female subjects were found for pulse risetime. Significance: Normative multi-site PPG risetime characteristics have been defined in over 300 subjects and are shown to increase with age linearly up to the 8th decade. In contrast, we have shown that heart rate has a clear inverse relationship with risetime for all measurement sites.

show abstract

Section: Discussionmentioning

confidence: 73%