Potential of tara (Caesalpinia spinosa) gallotannins and hydrolysates as natural antibacterial compounds

Aguilar‐Galvez, Ana; Noratto, Giuliana; Chambi, Flor; Debaste, Frédéric; Campos, David

doi:10.1016/j.foodchem.2014.01.110

Cited by 43 publications

(35 citation statements)

References 22 publications

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“…The IC 50 value of tara pod extract (468.2 μmol/L) was considerably higher than that of the hydrolysed extract. Similar results showing the increase in the antioxidant activity aft er tannin processing have previously been reported (16). Table 2 shows chemical composition, pH and cooking loss of pork meat batt ers.…”

Section: Extract Characterizationsupporting

confidence: 85%

“…65 % (by mass) of the fruit. Ground tara pods are rich in hydrolysable tannins (between 40-60 %, by mass), with gallic acid as the main constituent (16). Tara tannins are used in the manufacture of leather furniture, as a wine clarifi er, and as a source for obtaining the antioxidant gallic acid used in the oil industry (13).…”

Section: Introductionmentioning

confidence: 99%

“…Tara tannins are used in the manufacture of leather furniture, as a wine clarifi er, and as a source for obtaining the antioxidant gallic acid used in the oil industry (13). Anti-infl ammatory, antifungal, antibacterial and antiseptic properties have been att ributed to tara tannins (15)(16)(17)(18).…”

Section: Introductionmentioning

confidence: 99%

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Effect of tara (Caesalpinia spinosa) pod powder on the oxidative and colour stability of pork meat systems during chilled storage

Skowyra

Janiewicz

Salejda

et al. 2015

Food Technol. Biotechnol.

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SummaryThe eff ect of dried pods of Caesalpinia spinosa, known as tara, on pH, cooking loss, lipid oxidation, colour stability and texture of model meat systems stored at 4 °C for 21 days was investigated. Tara pod powder showing a potential antioxidant activity was added at 0.02, 0.04 and 0.08 % (by mass) directly to the pork batt er and compared with a synthetic antioxidant, butylated hydroxyanisole (BHA) and control (no added antioxidants). The addition of tara pod powder at 0.02 % was as eff ective as BHA (0.02 %) in retarding lipid oxidation in pork products during storage. Results showed that redness increased aft er the addition of tara pod powder. Specifi cally, 0.02 % of tara pod powder was eff ective in keeping the red colour of meat batt er stored under illumination at 4 °C for 48 h. Hardness of pork products was the lowest in samples manufactured with tara pod powder compared with control. Results highlight the potential of using tara pod powder as natural functional ingredient in the development of pork products with enhanced quality and shelf life.

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Section: Extract Characterizationsupporting

confidence: 85%

Section: Introductionmentioning

confidence: 99%

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Effect of tara (Caesalpinia spinosa) pod powder on the oxidative and colour stability of pork meat systems during chilled storage

Skowyra

Janiewicz

Salejda

et al. 2015

Food Technol. Biotechnol.

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“…This inhibitory action could be attributed to the tannins and flavonoids, since these constituents are well established as antimicrobial agents (Nenaah, 2013;Aguilar-Galvez et al, 2014;Bagla et al, 2014;Rodrigues et al, 2014;Zhang, Wang & Xu, 2014) and, they are present in the infusion and macerated extracts.…”

Section: Discussionmentioning

confidence: 99%

“…Tannins in general are phenolic compounds with antioxidant, astringent, antiparasitic, antiviral, and antibacterial properties (Aguilar-Galvez et al, 2014). There are several reports on the use of tannins in treating various diseases in humans, including snake bites, diarrhoea, gastric ulcers and wounds (Pereira et al, 2001;Palombo, 2006).…”

Section: Discussionmentioning

confidence: 99%

Antimicrobial activity of crude extracts and fractions of Vernonia polyanthes Less (assa-peixe) flowers

Waltrich

Hoscheid

Prochnau

2015

Rev. bras. plantas med.

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Antimicrobial activity of crude extracts and fractions of Vernonia polyanthes Less (assa-peixe) flowers. Vernonia polyanthes, known as "assa-peixe", is a plant native to Brazil, and the decoction or infusion of its flowers, roots and leaves are used in folk medicine, being considered sources of diuretic, balsamic, anti-rheumatic substances, and are used in cases of bronchitis and persistent cough. The aim of the study was to evaluate the antimicrobial activity of the extract/fractions obtained by methanol maceration and infusion of V. polyanthes flower, also including qualitative identification of flower compounds, through phytochemical evaluation, using colorimetric tests. Identification tests for the presence of anthraquinones, tannins, flavonoids, saponins and alkaloids were performed. Microbiological evaluation was made through agar diffusion assay, using Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa as test organisms. From the performed colorimetric tests it was possible to verify the presence of tannins and flavonoids in both extracts. Alkaloids were also observed in the macerated extract. The ethyl acetate fraction from the agar diffusion assay, from both extracts, presented microbial activity over Staphylococcus aureus. It was possible to qualitatively identify the floral compounds, and to show the differences between extraction methods, being methanol considered the best solvent to the extraction.Keywords: Assa-peixe; Cambará; Medicinal plants; Phytochemical profile. RESUMO: Atividade antimicrobiana de extrato bruto e de frações de flores de Vernonia polyanthes Less (assa-peixe).Vernonia polyanthes, conhecida como assa-peixe, é planta nativa do Brasil e suas flores, raízes e folhas, em decocção ou infusão, são empregadas na medicina caseira como diuréticas, balsâmicas, e anti-reumáticas, usadas nos casos de bronquite e tosse persistente. O objetivo do trabalho foi avaliar a atividade antimicrobiana do extrato/ frações obtidos por maceração em metanol e infusão de flores de V. polyanthes, incluindo também a identificação qualitativa dos compostos presentes nas flores, através da avaliação fitoquímica, empregando testes colorimétricos. Foram realizados testes para identificação de antraquinonas, taninos, flavonóides, saponinas e alcalóides. A avaliação microbiológica foi realizada por meio de ensaio de difusão em ágar, empregando Escherichia coli, Staphylococcus aureus e Pseudomonas aeruginosa. A partir dos testes colorimétricos foi possível verificar a presença de taninos e flavonóides em ambos os extratos. Ainda, no extrato macerado, foi observada a presença de alcalóides. No ensaio de difusão em ágar, a fração acetato de etila de ambos os extratos, apresentou atividade antimicrobiana sobre Staphylococcus aureus. Foi possível identificar qualitativamente os compostos da flor, demonstrando diferença entre as técnicas de extração, sendo que o metanol resultou em melhor poder extrativo.

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All‐in‐One Theranostic Platform Based on Hollow Microcapsules for Intragastric‐Targeting Antiulcer Drug Delivery, CT Imaging, and Synergistically Healing Gastric Ulcer

Wang

Xue

et al. 2022

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Bismuth‐containing therapies are suggested as first‐line and rescue alternatives for gastric ulcer (GU) treatment and Helicobacter pylori eradication. The current treatment strategy is called quadruple therapy and includes proton pump inhibitors, bismuth, and two broad‐band antibiotics. This fact may affect medication compliance, leading to a resistance rate of more than 25% to clarithromycin or metronidazole. To counter this, from the perspective of natural products, an intragastric‐targeting all‐in‐one theranostic platform is established: a drug carrier microcapsule composed of multiple synergistic antiulcer drugs, including bismuth, gallotannin, and antibiotics is obtained (BiG@MCs), and the therapeutic effects of BiG@MCs in rodent models are further evaluated. The results show that the BiG@MCs are spherical with homogeneous particle size (3 ± 0.5 µm) and can be response‐released to the acidic environment of the stomach (pH 2.0–3.0), preventing the premature release of the BiG@MCs in physiological conditions. It is worth noting that the bismuth component can be easily identified by computed tomography and other detection instruments, which provide the possibility for drug tracing. In summary, these results indicate that BiG@MCs provide a versatile intragastric‐targeting drug delivery platform for GU therapeutics.

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Potential of tara (Caesalpinia spinosa) gallotannins and hydrolysates as natural antibacterial compounds

Cited by 43 publications

References 22 publications

Effect of tara (Caesalpinia spinosa) pod powder on the oxidative and colour stability of pork meat systems during chilled storage

Effect of tara (Caesalpinia spinosa) pod powder on the oxidative and colour stability of pork meat systems during chilled storage

Antimicrobial activity of crude extracts and fractions of Vernonia polyanthes Less (assa-peixe) flowers

All‐in‐One Theranostic Platform Based on Hollow Microcapsules for Intragastric‐Targeting Antiulcer Drug Delivery, CT Imaging, and Synergistically Healing Gastric Ulcer

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