2023
DOI: 10.1007/s12602-023-10044-y
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Potential Probiotic Properties of Blautia producta Against Lipopolysaccharide-Induced Acute Liver Injury

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Cited by 22 publications
(15 citation statements)
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“…The genus Ruminococcaceae can increase the production of short-chain fatty acids (SCFAs), including acetic, propionic, and butyric acids, while reducing the release of inflammatory factors ( Wang et al, 2023 ). Additionally, Ruminiclostridium5 and Anaerotruncus have been linked to CD8+ and CD4+ T cells, and their abundance is negatively related to the levels of inflammatory TNF-α, IL-1β, and IL-6 ( Mao et al, 2023 ; Singh et al, 2023 ).…”
Section: Discussionmentioning
confidence: 99%
“…The genus Ruminococcaceae can increase the production of short-chain fatty acids (SCFAs), including acetic, propionic, and butyric acids, while reducing the release of inflammatory factors ( Wang et al, 2023 ). Additionally, Ruminiclostridium5 and Anaerotruncus have been linked to CD8+ and CD4+ T cells, and their abundance is negatively related to the levels of inflammatory TNF-α, IL-1β, and IL-6 ( Mao et al, 2023 ; Singh et al, 2023 ).…”
Section: Discussionmentioning
confidence: 99%
“…Similar to the above studies, the current study found that L. reuteri alleviated hepatic I/R-induced injury by a mechanism that may be related to the protection of intestinal barrier function and maintenance of gut microbiota homeostasis. Blautia , with potential probiotic properties, alleviates LPS-induced acute hepatic injury [ 32 ]. Lactobacillus acidophilus and Bifidobacterium may protect against myocardial ischemia-reperfusion [ 33 ].…”
Section: Discussionmentioning
confidence: 99%
“…Several Blautia species have recently been identified to have beneficial effects on host function, including the suppression of Vibrio cholera colonization 48 , improving inflammatory responses in a DSS mouse model 49 , ameliorating obesity and type-2 diabetes 50 and protecting against enteric viral infection 51 , despite being a rather low-abundance gut bacterium. The molecular mechanism has not been identified in all cases, but SCFA production was shown to be an important factor for some of these observations.…”
Section: Discussionmentioning
confidence: 99%