This study aims to report the handling of endometritis in a dairy cow at Koperasi Agro Niaga Jabung, Malang, Indonesia. A Holstein Friesian cross heifer was diagnosed at 258 days pregnant and clinically suffering from Foot and Mouth Disease. On the 266th day of pregnancy, the fetus died, an abortion was diagnosed, and the delivery was assisted by the veterinarian. Furthermore, the cow was treated with 15 mL oxytetracycline intramuscularly. The next day, the veterinarian treated the retained placenta. On the third day after the abortion, the farmer reported that the cow had vaginal discharge which was cloudy white, reddish and smelled bad. The veterinarian treated the cow with an injection of 15 mL of Oxytetracycline. On the sixth day after the abortion, the farmer reported that vaginal discharge still coming out again. Clinical symptoms were, thick, purulent, cloudy, pink discharge from the vagina that hanged in the vulva area and smelled bad. Physical examination showed a body temperature of 40°C, and rectal palpation revealed the uterine wall to be thick, hard, stiff, and getting warmer. Furthermore, the cow was given intrauterine flushing with 1% povidone-iodine (diluted in distilled water), followed by intrauterine administration of 15 mL Oxytetracycline, analgesics, antipyretics, and antispasmodics. Fifteen mL of vitamin B12, ATP, and minerals (Magnesium, Potassium, Sodium selenite) was injected intramuscularly.