Potential relationship of dyslipidemia with dietary patterns in oral lichen planus patients-A case-control study

Li, Kaiyi; Li, Chunlei; Hua, Hong; Song, Zhiqing

doi:10.1016/j.jds.2023.01.006

Cited by 5 publications

(7 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“… 6 , 11 , 12 The prevalence of dyslipidemia in our study was 65% which is similar to Shingla et al. 26 In our study, dyslipidemia was significantly associated with LP which is in accordance with studies reported previously. 12 , 25 , 27 …”

Section: Discussionsupporting

confidence: 91%

“…A permanent high-fat diet promotes hyperinsulinemia, insulin resistance, dyslipidemia, and increased production of oxidative stress which might lead to Metabolic Syndrome in these patients. 25,26 Dyslipidemia has been reported in around 35.9%-81.4% of patients with LP as reported in the literature which is due to cytokine-mediated lipolysis. 6,11,12 The prevalence of dyslipidemia in our study was 65% which is similar to Shingla et al 26 In our study, dyslipidemia was significantly associated with LP which is in accordance with studies reported previously.…”

Section: Discussionmentioning

confidence: 99%

“…25,26 Dyslipidemia has been reported in around 35.9%-81.4% of patients with LP as reported in the literature which is due to cytokine-mediated lipolysis. 6,11,12 The prevalence of dyslipidemia in our study was 65% which is similar to Shingla et al 26 In our study, dyslipidemia was significantly associated with LP which is in accordance with studies reported previously. 12,25,27 Various patterns of dyslipidemia have been reported in patients with LP.…”

Section: Discussionmentioning

confidence: 99%

“…It has been stated in the literature that oral LP was more common in patients with bad eating habits that is, diets rich in animal fats (e.g red meat, processed and fried food). A permanent high‐fat diet promotes hyperinsulinemia, insulin resistance, dyslipidemia, and increased production of oxidative stress which might lead to Metabolic Syndrome in these patients 25,26 …”

Section: Discussionmentioning

confidence: 99%

“…A permanent high‐fat diet promotes hyperinsulinemia, insulin resistance, dyslipidemia, and increased production of oxidative stress which might lead to Metabolic Syndrome in these patients. 25 , 26 …”

Section: Discussionmentioning

confidence: 99%

See 4 more Smart Citations

Metabolic syndrome in patients with lichen planus: A case‐control study

Mathur,

Thakur,

Jaiswal

et al. 2023

Skin Health and Disease

View full text Add to dashboard Cite

BackgroundLichen Planus (LP) is a chronic dermatosis affecting the skin and mucous membranes. Chronic inflammation and oxidative stress in patients with LP is a trigger predisposing to Metabolic Syndrome.ObjectivesTo study the association of Metabolic Syndrome in patients with LP.Materials and MethodsA hospital‐based prospective case‐control study was conducted from April 2021 to January 2023 including 75 histopathologically confirmed patients with LP and 82 age and sex‐matched controls according to the inclusion and exclusion criteria. Metabolic Syndrome was diagnosed using Modified National Cholesterol Education Programme Adult Treatment Panel III criteria. Statistical analysis of the data was performed using Statistical Package for the Social Sciences software, version 26. The chi‐square test was used for data analysis.ResultsThe majority (30.6%) of the patients belonged to the age group 31–40 years. The mean age of patients with LP was 46.13 ± 14.9 years. Female predominance (69.3%) was observed in our study. Patients with classic LP (54.6%) were predominantly observed. Metabolic Syndrome was significantly prevalent in LP patients than in controls (32% vs. 13.4%, p = 0.005, OR 3.037) and was significantly associated with morphology (only oral mucosal involvement, 61.5%, p 0.027, OR 3.9), severity (severe LP, 58.6%, p < 0.001, OR 7.79), and duration of the disease (≥6 months, 55.5%, p 0.001, OR 5.42). 71% of Metabolic Syndrome was observed in females (p 0.847). Among patients with metabolic syndrome, the majority belonged to the age group between 31 and 40 years (37.5%, p 0.378). Systolic and Diastolic Blood Pressure values (≥130/85 mm of Hg), Serum Triglycerides (≥150 mg/dl), and Low‐Density Lipoprotein (>130 mg/dl) were significantly elevated, and High‐Density Lipoprotein (<40 mg/dl) was significantly low in LP than in controls (p < 0.05).ConclusionThe study showed a significant association of Metabolic Syndrome in patients with LP. Thus, patients with LP need to be screened to avoid complications associated with Metabolic Syndrome that is, Diabetes Mellitus, Cardiovascular Disease, colorectal cancer, and stroke.

show abstract