2024
DOI: 10.1016/j.talanta.2023.125063
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Potential-resolved electrochemiluminescence biosensor for simultaneous determination of multiplex miRNA

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Cited by 6 publications
(2 citation statements)
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“…Electrochemiluminescence (ECL), as an ideal combination of electrochemical and spectroscopic techniques, possesses fascinating merits including near-zero background, high sensitivity, and excellent spatiotemporal controllability. These appealing superiorities make the ECL technique receive tremendous attention in biosensing, environmental monitoring, and other areas of analytical chemistry. , Nonetheless, the conventional ECL detection system usually involves the single-signal mode, which is vulnerable to other interferences derived from intrinsic or extrinsic factors, resulting in false positive or negative responses. To overcome the inherent defects, various ratiometric ECL sensing strategies with self-rectification functions have been developed, mainly including dual-wavelength and dual-potential detection modes. Compared with the spectrum-resolved ECL detection, the potential-resolved strategies exclude intricate optical instruments and operations. , Nevertheless, it remains a challenge to design a pair of advanced ECL emitters to achieve dual-potential ratiometric ECL sensing.…”
Section: Introductionmentioning
confidence: 99%
“…Electrochemiluminescence (ECL), as an ideal combination of electrochemical and spectroscopic techniques, possesses fascinating merits including near-zero background, high sensitivity, and excellent spatiotemporal controllability. These appealing superiorities make the ECL technique receive tremendous attention in biosensing, environmental monitoring, and other areas of analytical chemistry. , Nonetheless, the conventional ECL detection system usually involves the single-signal mode, which is vulnerable to other interferences derived from intrinsic or extrinsic factors, resulting in false positive or negative responses. To overcome the inherent defects, various ratiometric ECL sensing strategies with self-rectification functions have been developed, mainly including dual-wavelength and dual-potential detection modes. Compared with the spectrum-resolved ECL detection, the potential-resolved strategies exclude intricate optical instruments and operations. , Nevertheless, it remains a challenge to design a pair of advanced ECL emitters to achieve dual-potential ratiometric ECL sensing.…”
Section: Introductionmentioning
confidence: 99%
“…ECL sensor, as a detection device combining ECL analysis method and sensing technology, possesses numerous advantages in substance analysis [1][2] . ECL sensors enable quantitative analysis of target substances by utilizing changes in ECL signals caused by enhancement or inhibition of the ECL process [3][4] . The advancement of efficient, budget-friendly, and easily labeled ECL materials is attractive for the creation of highly sensitive ECL sensors, which find applications in clinical diagnostics, biosecurity, environmental surveillance, and other fields [5][6] .…”
Section: Introductionmentioning
confidence: 99%