Potential risk factors for Varicella‐zoster virus reactivation after COVID‐19 vaccination

Commentary on “Potential risk factors for Varicella‐zoster virus reactivation after COVID‐19 vaccination”

“…The shingles caused by reactivation of VZV may occur spontaneously or be triggered by fever, immunosuppression, stress, or trauma 7,8 . As a possible explanation for VZV reactivation, in an agreement with May Lee et al, we also support the hypothesis of an immunomodulation mechanism triggered by vaccination 1 …”

“…We read with great interest the article “Potential risk factors for Varicella‐zoster virus reactivation after COVID‐19 vaccination” by May Lee et al 1 recently published in the Journal of Cosmetic Dermatology. As stated by the authors, various vaccines have been developed to control the spread of the virus during the COVID‐19 pandemic period, and more and more attention is paid to the negative effects of their application.…”

“… 7 , 8 As a possible explanation for VZV reactivation, in an agreement with May Lee et al, we also support the hypothesis of an immunomodulation mechanism triggered by vaccination. 1 …”

Zoster sine herpete following BNT162b2 mRNA COVID-19 vaccination in an immunocompetent patient

“…Many cases of herpes zoster following COVID-19 vaccination were reported [3] , [7] , to our knowledge, this case is the first case of ZSH following mRNA vaccination. Among herpes zoster cases following COVID-19 vaccination, several cases have been reported after mRNA vaccination [2] , [3] , [4] . However, it might simply be due to the high frequency of mRNA vaccination worldwide.…”

“…During the COVID-19 pandemic, mRNA vaccination has been conducted worldwide, which has demonstrated a high efficacy rate with an acceptable safety profile [1] . Recently, it has been suggested that herpes zoster potentially increases following mRNA COVID-19 vaccination [2] , [3] , [4] although it is uncertain if mRNA COVID-19 vaccine significantly induced that [5] .…”