Potential Role of Computed Tomography Volumetry in Size Matching in Lung Transplantation

Size-matching in lung transplantation by computed tomography for end-stage interstitial disease: a retrospective analysis

“…Indeed, by improving size matching with CT volume, we may better anticipate short and long-term outcomes. Prabhu et al have demonstrated, by comparing pTLC ratio (calculated by dividing the donor pTLC by the recipient pTLC) with volumetric ratio (calculated by dividing the donor pTLC by the recipient ctTLC), that undersizing was independently associated with significantly lower odds of PGD unlike the pTLC ratio ( 33 ): this was confirmerd by Vazquez Guillamet et al who found that larger donor and smaller recipient lung volumes estimated by CT predicted a need for surgical graft reduction and were associated with higher PGD grade ( 34 ). Concerning long-term outcomes, using the volumetric ratio, oversizing was independently associated with a higher risk of death unlike the pTLC ratio ( 33 ).…”