Potential role of fetal cardiac evaluation with magnetic resonance imaging: preliminary experience

Manganaro, Lucia; Savelli, Sara; Maurizio, Marco Di; Perrone, Anna; Tesei, Jacopo; Francioso, A.; Angeletti, Marco; Coratella, F.; Irimia, D.; Fierro, Francesca; Ventriglia, Flavia; Ballesio, Laura

doi:10.1002/pd.1945

Cited by 57 publications

(47 citation statements)

References 29 publications

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“…Due to its noninvasive nature, this present study is far more practicable, particularly in relation to human subjects. Compared with images of prior studies (17)(18)(19), the visualization in this study of the aforementioned anatomical structures demonstrated considerable improvements in the adequacy of the visualization. Prior studies described difficulties with the imaging of main cardiac outflow vessels, such as the aorta with its valve (19).…”

Section: Discussionmentioning

confidence: 86%

“…Compared with images of prior studies (17)(18)(19), the visualization in this study of the aforementioned anatomical structures demonstrated considerable improvements in the adequacy of the visualization. Prior studies described difficulties with the imaging of main cardiac outflow vessels, such as the aorta with its valve (19). In contrast to such studies, the current study enabled the aortic valve to be visualized, both in open and in closed condition, using the novel triggering method (Fig.…”

Section: Discussionmentioning

confidence: 86%

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Cardiac MRI of the fetal heart using a novel triggering method: Initial results in an animal model

Yamamura

Kopp

Frisch

et al. 2012

Magnetic Resonance Imaging

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Purpose: To investigate MRI of the fetal heart by way of a novel triggering method with the use of an MR-compatible cardiotocography (CTG) in an animal model. Materials and Methods:Fetal cardiac MRI was performed on four pregnant ewes on a 1.5 Tesla (T) MR system. A CTG was rendered MR compatible and its signal was used for the triggering of the fetal heart to perform cardiac cine MRI of the fetal heart with maternal freebreathing with cine steady-state free precession. The left ventricular volume and function were measured from the short-axis (view). The image quality of anatomical structures was assessed.Results: All cardiac valves and the foramen ovale could be visualized. Myocardial contraction was depicted in cine sequences. The average blood volume at the end systole was 1.7 mL (SD 6 0.12). The average volume at the end diastole was 4.6 mL (6 0.4); thus the average stroke volumes of the left ventricle were 2.87 mL (6 0.31) with ejection fractions of 60.53% (6 4.17). Conclusion:The newly developed MR compatible CTG could be used as a tool for cardiac triggering method of the fetal heart. This novel device might help fetal cardiac MRI technology in the future. THE RAPID DEVELOPMENT of cardiac MR imaging in the past few years has enabled many different investigations, for example investigations into coronary arteries and myocardial infarctions. In practice, twodimensional (2D) CINE steady-state free precession (SSFP) imaging is the most reliable and frequently used technique for left ventricular (LV) function assessment. To assess the LV function correctly, speed as well as synchronization of data acquisition with the cardiac cycle are required, so that artifacts due to cardiac motion and flow constraints that dictate the viable window for data acquisition are avoided. To avoid the artifacts caused by cardiac motion, it is customary that either finger pulse oximetry or electrocardiography (ECG) triggering/gating techniques are used so that data acquisition can be synchronized with the cardiac cycle.Although the use of MR imaging during pregnancy is limited to the second and third trimester, its diagnostic value has been increasing in recent years. In the field of fetal MR imaging, the evaluation of the fetal heart is one of the greatest challenges. Nowadays, the gold standard in fetal cardiac imaging is the use of ultrasound (US), because it can be obtained during the entire pregnancy; it is easy to use and thus more practicable. Both the measurement of the cardiac volume and the evaluation of volumetric changes with US are possible, and the technology has been improving. Because cardiac chambers do not lend themselves to geometric assumptions, it has always been difficult to calculate their dimensions, even though studies have shown that 3D US has a better reproducibility than 2D (1-4). To be able to do so, it is necessary to trace the volume of the cardiac chambers manually, due to the appearance of various US specific artifacts, such as speckles and acoustic shadowing, which appear when traced automaticall...

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Section: Discussionmentioning

confidence: 86%

Section: Discussionmentioning

confidence: 86%

Cardiac MRI of the fetal heart using a novel triggering method: Initial results in an animal model

Yamamura

Kopp

Frisch

et al. 2012

Magnetic Resonance Imaging

View full text Add to dashboard Cite

show abstract

“…According to a report of 32 fetuses assessed for congenital heart disease, fetal MRI permitted identification of extracardiac anomalies associated with cardiac abnormalities. The authors document that MRI detected adjunctive fetal anomalies (particularly in CNS and neck) that US did not depict (Manganaro et al, 2008).…”

Section: Fetal Cmr Findings In Complex Congenital Heart Disease (Chd)mentioning

confidence: 99%

“…In-utero MR imaging of the fetal heart 2.2.1 Feasibility and patients' selection MRI of the fetal heart is feasible (Saleem, 2008); however, it has not been thoroughly investigated with only few reports in literature most of them in the form of case reports or preliminary experiences (Gorincour et al, 2007;Kivelitz et al, 2004;Manganaro et al, 2008). We will depend in discussion of MRI of fetal heart in this chapter on findings from our study of 298 pregnancies at high risk for CHD that were enrolled sequentially from September 2003 to August 2010 in our institutional review board-approved study.…”

Section: 2mentioning

confidence: 99%

Fetal Cardiac Magnetic Resonance (CMR)

Saleem¹

2012

Echocardiography - New Techniques

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“…Delayed myocardial enhancement magnetic resonance can serve to delineate the location and transmural extent of endocardial fibroelastosis in infants, thus providing an accurate roadmap for the surgical planning of fibroelastosis resection and for monitoring the results . Magnetic resonance is also proposed to aid fetal ultrasonography in the prenatal assessment of congenital cardiac malformations (Manganaro et al, 2008).…”

Section: Magnetic Resonancementioning

confidence: 99%