Potential Tamarindus indica L. and Curcuma domestica as Immunomodulators for the improvement of Lymphocyte Cells

Abstract

When the body's resistance is weak, the body is unable to fight viruses, bacteria, and germs that cause disease. As a result, humans become more susceptible to disease. To prevent it from happening, natural ingredients have long been used as a traditional medicine in Indonesia and almost all countries in the world. Some of these traditional medicines are Tamarindus indica L. and turmeric (Curcuma domestica). This study used mice (Mus musculus) aged 1-2 months. There were five group treatments used in this study. In group 1(G1), the treatment was carried out by feeding and aqua dest as much as 0.25ml (control). While group 2(G2) treatment was with feeding and stimuno as much as 0.25ml, group 3 (G3) was treated by feeding and infusing Tamarindus indica L and Curcuma domestica with a 12.5% concentration. Group 4(G4) treatment was undergone by feeding and infusing Tamarindus indica L and Curcuma domestica with a 25% concentration. Finally, group 5(G5) treatment was performed by feeding and infusing Tamarindus indica L and Curcuma domestica with a higher concentration, i.e., 37.5%. The results showed that the number of lymphocytes increased. It can be seen in the G3, G4, and G5 treatments that have the same value as the comparison of the manufacturer's immunomodulatory supplement (G2). Infusing Tamarindus indica L and Curcuma domestica have the potential to be used as immunomodulators at the lowest doses.