“…It has been proposed that miRNAs might be involved in controlling inflammation during COVID-19 (Aslani et al, 2021;Gasparello et al, 2021;Houshmandfar et al, 2021;Matarese et al, 2020;Plowman and Lagos, 2021). Theoretical CC/miRNA regulatory networks have been proposed but not validated (Khokhar et al, 2022), whereas the potential of miRNA-like therapeutics has also been suggested (Ahn et al, 2021;Dash et al, 2021;Hum et al, 2021;Park et al, 2021). Of note, initial studies have identified potential changes in miRNA expression in COVID-19 and signatures from targeted testing of 41 miRNAs have been linked to ICU treatment and mortality in a Spanish cohort (de Gonzalo-Calvo et al, 2021).…”