Potential Use of Saga Leaf Extract (Abrus precatorius) as Anti Bacteria Aeromonas hydrophila by in Vitro

Abstract

Many diseases are caused by bacterial pathogens, for example, Aeromonas hydrophila. One alternative that can be done to overcome this problem is to use saga leaves (Abrus precatorius) which have bioactive ingredients as antibacterial ingredients. The aims of this study were to determine the antibacterial activity of saga (A. precatorius) leaf extract, to study the character and structure of bacteria inhibited by saga (A. precatorius) leaf extract and to study the bioactive components contained in saga (A. precatorius) leaf extract. The results of the disc test showed that the average inhibition zone was 14,29 mm while the MIC test results showed that at the dose 1 mg/L capable of inhibiting bacterial growth (bacteriostatic) and dose 10 mg/L It has been able to kill bacteria (bactericidal). Crude extract of saga leaf extract (A. precatorius) affects the character and structure of A. hydrophila bacteria by damaging the cell walls and cell membranes of bacteria. The results of Infrared Spectrophotometry analysis of saga (A. precatorius) leaf extract and Ultra Violet Spectrophotometry analysis with 96% absorption ethanol were suspected to contain flavonoid compounds

Pengaruh Konsentrasi Ekstrak Biji Kakao Terhadap Diameter Zona Bening Pada Bakteri Streptococcus Mutans

“…Cacao bean production is almost the third largest in the world, seed content such as flavonoids, catechins and bioactive compounds can be used as potential antibacterial alternatives, by extracting the seeds can inhibit bacterial growth (Kenitasari et al, 2023), besides that the bioactive components of flavonoids, polyphenols, catechins, and saponins can prevent streptococcus mutans can be formed more slowly, in addition to the significant antibacterial effect on cocoa against Fusobacterium nucleatum, Porphyromonas gingivalis, and Prevotella intermedia (Ben Lagha et al, 2021;Cinar et al, 2021;Jean-Marie et al, 2021).…”