Potentially Inappropriate Medication use in the Elderly in a Tertiary Care Centre in South India

Christopher, Alwin; Pranita, Vanjare; Mathews, Kuruvilla Prasad; Viggeswarpu, Surekha; Kg, Gopinath; Gowri, Mahasampath

doi:10.35262/jiag.v14i3.130-135

Cited by 3 publications

(2 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This study is a part of Amirkala Health and Ageing Project (AHAP) conducted as a cohort study on older adults since 2011. Age ≥60 years, residence in Amirkala county, and willingness to participate in the study were considered as inclusion criteria, while the lack of sufficient information was considered as the exclusion criterion [9]. The required information was collected by a two-part questionnaire with 17 items; the first part consists of 5 questions about the demographic characteristics of participants (age, marital status, level of education, employment status, smoking, underlying diseases, etc.)…”

Section: Methodsmentioning

confidence: 99%

Inappropriate Medication Use and Related Factors in the Elderly Living in Northern Iran

Dadashihaji

2021

Salmand

View full text Add to dashboard Cite

Objectives: Older people are more prone to chronic diseases and are being treated than other age groups; as a result, they use more drugs that may be inappropriate and lead to adverse drug reactions. This study aimed to determine the rate of inappropriate drug use using the Beers criterion among the elderly in Amirkola City. Methods & Materials: The current descriptive-analytical study is part of the comprehensive plan "Study of the health status of the elderly in the Amirkola City” AHAP" (No.: 892917) which has been conducted as a Cohort study since 2011 on all people aged 60 and over in the Amirkola City, north of Iran. Necessary information was collected by a trained person using standard questionnaires that included the number, type and duration of drug use. The collected data were analyzed after entering the SPSS statistical software using Chi-square, Fisher's Exact Test, and Logistic Regression to evaluate the status of inappropriate drug. P-value=0.05 was considered as a significant level. Results: The Mean±SD age of the elderly was 69.71±7.47 years. Prevalence of inappropriate drug use and drugs that should use by caution among the elderly was 37.58% and 29.85%, respectively. Glibenclamide (12.7%), Diclofenac (8.8%) and Clidinium C (5.4%) were among the most inappropriate drugs used in this population. The highest drug-drug interaction was related to the simultaneous use of two anticholinergic drugs. There was a statistically significant relationship between inappropriate drug use with gender, age, education level, employment status and marriage status (P<0.05). Conclusion: The rate of inappropriate drug use among the elderly in Amirkola is high compared to many other studies that expose the elderly to adverse drug reactions.

show abstract

Section: Methodsmentioning

confidence: 99%

Inappropriate Medication Use and Related Factors in the Elderly Living in Northern Iran

Dadashihaji

2021

Salmand

View full text Add to dashboard Cite

show abstract

“…The study was conducted on hospitalized elderly people in India. The prevalence of using PIMs according to the Beers criteria was reported as 33.2% (8). The results of a study among elderly patients referred to pharmacies in Tehran estimated the prevalence of PIMs as 26.0% according to the Beers' criteria.…”

Section: Introductionmentioning

confidence: 99%

Frequency of Potentially Inappropriate Medications in Iranian Elderly Hospitalized Patients

Sharifzadeh Kermani,

Borhaninejad,

Sepehri

et al. 2024

Health and Development Journal

View full text Add to dashboard Cite

Background: Potentially inappropriate medications (PIMs) should not be prescribed to the elderly due to low effectiveness and adverse drug reactions. This study was conducted to determine the frequency of PIMs in the elderly admitted to educational hospitals in Kerman, in 2023. Methods: This cross-sectional study was conducted on 1500 elderly patients hospitalized in educational hospitals. The data collection forms were completed according to the health information system (HIS) of the hospital, which includes the patient’s age and gender, drug information, and the name of the hospital and ward. PIMs prescriptions were assessed according to Zhan’s criteria. Statistical analyses were performed using SPSS version 20.0. The results were presented as mean±standard deviation (SD) and frequencies (percents). Results: Nearly 17.8% (n=267) of patients were treated with at least one PIMs included in the Zhan criteria. Among 331 PIMs used for patients, 43.5% (n=144), 23.3% (n=77), and 33.2% (n=110) of drugs were classified as always avoid, rarely appropriate, and some indication, respectively. Sedative-hypnotics, opioids, and antihistamines were the most prevalent PIMs with 29.5% (n=98), 25.4% (n=84), and 23.3% (n=77) frequency. Approximately 71.4% (n=10) of patients who were admitted to the Oncology ward, and 38.9% (n=33) of patients who were admitted to the Critical Care Unit were treated with at least one PIMs. Conclusion: Today PIMs are a problem for elderly patients. Paying attention to PIMS in oncology, and critical care unit wards is important. More attention should be paid to sedative-hypnotics, opioids, and antihistamines as the most frequently prescribed PIMs.

show abstract

Prevalence of potentially inappropriate medications in Iranian elderly hospitalized patients

Kermani

Borhaninejad

Sepehri

et al. 2023

Preprint

View full text Add to dashboard Cite

Background: Population aging is a health challenge in the world and Iran. Potentially inappropriate medications (PIMs) should not be prescribed to the elderly due to low effectiveness and adverse drug reactions. There are various tools for screening PIMs including Zhan's criteria. This study was conducted to determine the frequency of PIMs in the elderly admitted to teaching hospitals in Kerman, in 2023. Methods: This cross-sectional descriptive study was conducted on 1500 elderly patients hospitalized in educational hospitals in Kerman, Iran, 2023. The inclusion criteria were determined as age> 60 years. Patients with incomplete electronic information were excluded from the study. Patients were selected using stratified multistage sampling method. The data collection forms were completed according to the Health Information System (HIS) of the hospital, which includes the patient's age and gender, drug information, and the name of the hospital and ward. PIMs prescriptions were assessed according to Zhan's criteria. Statistical analyses were performed using SPSS version 20.0. The results were presented as mean ± standard deviation (SD) for quantitative data and frequencies (percents) for qualitative data. Results: Nearly 17.79% of patients were treated with at least one PIMs included in the Zhan criteria. Among them, one PIMs was found in 76.02%, two PIMs were detected in 19.86%, and three or more PIMs were found in 4.12% of patient’s records. Patients who were admitted to the surgical ward (47.5%), Critical Care Unit (34.2%), and infectious diseases ward (25.3) had the most percent of prescribing PIMs. Totally, 331 PIMs were used for patients. Considering the classification of Zhan, 43.51%, 23.26%, and 33.23% of drugs were classified as always avoid, rarely appropriate, and some indication, respectively. Considering pharmaceutical categories, sedative-hypnotics, opioids, and antihistamines were the most prevalent PIMs. Among inappropriate drugs, pethidine, chlordiazepoxide, Hyoscine, Chlorpheniramine, and Indomethacin were the most prevalent PIMs, respectively. Conclusions: PIMs are still frequently experienced by elderly patients in Iranian hospitals. Specifically, physicians in the surgical ward, Critical Care Unit, and infectious diseases ward need to be more aware of PIMs. More attention should be paid to sedative-hypnotics, opioids, and antihistamines as the most frequently prescribed PIMs.

show abstract

Potentially Inappropriate Medication use in the Elderly in a Tertiary Care Centre in South India

Cited by 3 publications

References 18 publications

Inappropriate Medication Use and Related Factors in the Elderly Living in Northern Iran

Inappropriate Medication Use and Related Factors in the Elderly Living in Northern Iran

Frequency of Potentially Inappropriate Medications in Iranian Elderly Hospitalized Patients

Prevalence of potentially inappropriate medications in Iranian elderly hospitalized patients

Contact Info

Product

Resources

About