Potentially inappropriate prescribing of drugs in elderly patients on chronic hemodialysis treatment

Abstract

Adequate consideration of potential risk factors, as well as the implementation of valid criteria for assessment of PIP, are just some of the measures that would contribute to solving complex therapeutic problems and designing strategies for rational prescribing according to the individual characteristics of patients. .

Potentially inappropriate prescribing among older patients and associated factors: comparison of two versions of STOPP/START criteria

“…The number of comorbidities showed a statistically significant association with both START v1 and START v2 criteria (Table IV). Similarly, a positive influence of the number of comorbidities or comorbidity index was recorded in some studies using either v1 or v2 criteria (Anrys et al, 2018;Bo et al, 2019;Gallagher et al, 2011a;Ma et al, 2020;Nedin Rankovic et al, 2018), but not in others (Blanco-Reina et al, 2019;Counter et al, 2018). Interestingly, the number of comorbidities was also a significant predictor for STOPP v2 criteria, but not v1.…”

“…Previously, predictors of potentially inappropriate prescribing were investigated in numerous studies with diverse designs, populations, and methodology, but usually not simultaneously for both versions of the criteria. Various studies have identified polypharmacy and number of medications as a predictor of PIMs based on the updated or original version of the criteria (Anrys et al, 2018;Blanco-Reina et al, 2016;Blanco-Reina et al, 2019;Bo et al, 2019;Buda et al, 2020;Counter, Marija Jovanović, Milena Kovačević, Aleksandra Catić-Đorđević, Milica Ćulafić, Nikola Stefanović, Branka Mitić, Katarina Vučićević, Sandra Vezmar Kovačević, Radmila Veličković-Radovanović, Branislava Miljković Millar, McLay, 2018;Gallagher et al, 2011a;Hill-Taylor et al, 2013;Ma et al, 2020;Nedin Rankovic et al, 2018;Projovic et al, 2016;Rogero-Blanco et al, 2020;Thomas, Thomas, 2019;Vezmar Kovacevic et al, 2014).…”