Potentiation of the Contractile Response of Isolated Aortae to Transmural Stimulation by Angiotensin

Toda, Noboru

doi:10.1254/jjp.23.871

Cited by 3 publications

(1 citation statement)

References 6 publications

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“…We cannot explain the discrepancy between the findings of T oda [11] and the present study. He was able to demonstrate a presynaptic, but no postsynaptic, effect of angiotensin (5 x 10 "-1 x 10'®) in rabbit aorta.…”

contrasting

confidence: 99%

Adrenergic Potentiation by Angiotensin II in Isolated Canine Cutaneous Arteries: Effect of Bathing Media and Calcium

Povolny¹,

Jung²,

Kraft³

et al. 1977

J Vasc Res

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Contractions were elicited by field stimulation and norepinephrine in canine cutaneous arteries in Krebs-bicarbonate and Krebs-Tris media and the effect of angiotensin II, 1 × 10^–7 m, on these responses was determined. The absolute magnitude of the field stimulation responses was much greater in the bicarbonate buffer. Angiotensin caused potentiation in both media of the responses to field stimulation and norepinephrine. In Tris buffer with 5 mM calcium the responses to field stimulation and norepinephrine were greater than in 2.5 mM calcium, however; the degree of potentiation caused by angiotensin was similar at both calcium concentrations. The angiotensin potentiating effect in vitro appears to involve a postsynaptic action of the polypeptide which is not affected by alteration of calcium concentration or the medium.

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confidence: 99%