Potentiometric measurement of urinary iodine concentration in patients with thyroid diseases with and without previous exposure to non-radioactive iodine

Abstract

Iodine-specific ISE-based potentiometric methods can be successfully applied as an alternative to existing methods in patients with thyroid diseases. The promising characteristics of the method need to be confirmed in future larger prospective studies.

Successful Treatment of Amiodarone-induced Thyrotoxicosis Type 1 in Combination with Methimazole and Potassium Iodide in a Patient with Hashimoto's Thyroiditis

“…The urinary iodine concentration has been reported to be useful for differentiating destructive thyroiditis from Graves' disease (18). In the present case, however, it was not tested because elevated urine iodine excretion after amiodarone treatment negates its diagnostic value (18,19). Although the FT3/FT4 ratio also has been reported to be helpful for differentiating painless thyroiditis from Graves' disease (20), the present patient's severe comorbid conditions, including lethal arrhythmia and heart failure, would have modified the FT3/FT4 ratio in this case.…”