Background: Pott`s fracture is one of the most common lower limb fractures representing a significant percentage of the trauma workload. Aim of the study: The study aimed to evaluate the effect of instructional guidelines for patients with pott's fracture to improve physical activity and functional ability. Design: Quasi-experimental design was utilized. Setting: The study was accomplished in orthopedic Unit at Mansoura University Emergency & Accident Hospital then patients were followed up at orthopedic outpatient clinics. Subjects: Purposive sample of 52 patients at orthopedic department selected according to inclusion and exclusion criteria. Tools: Three tools were used. Assessment interview questionnaire sheet includes demographic and health relevant data, knowledge assessment sheet and Baird and Jackson Scoring System (BJSS). Results: Showed statistically significant improving of both physical activity and functional ability level after the application of instructional guidelines. Conclusion: The study concluded that there was an effective effect of instructional guidelines on improving physical activity and functional ability among pott`s fracture patients. Recommendation: It was recommended that Handout with instructional guidelines should be distributed and be available for every Pott`s fracture patient admitted to orthopedic department, which are supported by the presence of a nutritionist and exercise trainer.