Pouchitis After Ileal Pouch-Anal Anastomosis for Ulcerative Colitis

Abstract

Pouchitis is a most frequent complication in patients with ileal pouch, it occurs at least 50% of them once in a lifetime. However, pouchitis can be treated fast and effectively. Twenty per cent of patients with chronic pouchitis have unfavourable prognosis because of antibiotic resistance and antibiotic dependence. It is hard to choose an effective treatment in this group of patients, which should include induction and maintenance therapy. Ineffective conservative treatment indicates a necessity of detection of secondary causes of pouchitis. Currently, there is not enough experience and less understanding of the causes of pochitis to decrease its incidence. Further studies are needed.