“…2,3 In recent studies, a new Doppler index -the ratio of E to e' multiplied by peak systolic mitral annular velocity (s') derived by Doppler tissue imaging (E/(e'xs'), is demonstrated to be superior to E/ e', e', s', or E in sinus rhythm (SR) patients and has high diagnostic accuracy, particularly in patients with intermediate values for E/e' ratio (8)(9)(10)(11)(12)(13)(14)(15). 4 Elevated E/e' ratio and to a lesser extent E/(e'xs') have been confirmed as beneficial predictors of new-onset AF, AF recurrence after electrical cardioversion (ECV), and worse outcomes in patients with various heart diseases. [5][6][7][8][9][10] A comprehensive systematic review by D. Kotecha reported that diastolic function indices, particularly E/e', are valid and reproducible in patients with AF when the appropriate cardiac cycles are carefully selected.…”