Povidone-Iodine sclerosis of pelvic lymphoceles: A prospective study

Abstract

Twelve patients presented for percutaneous catheter drainage of 13 postoperative pelvic lymphoceles. Six patients with 7 lymphoceles were treated with povidone-iodine sclerosis prior to catheter removal. Only 1 lymphocele (which continued to drain large amounts of fluid during and after the sclerosis procedure) recurred. Six patients with 6 lymphoceles had their percutaneous catheters removed without sclerosis. Fluid collections recurred in 3 instances, necessitating repeat percutaneous drainage (2 patients) or surgery (1 patient). Percutaneous therapy is the treatment of choice for patients with postoperative lymphoceles. Povidone-iodine sclerosis is often effective in preventing reaccumulation of fluid once the lymphocele cavity is collapsed.

Congenital chylothorax: current perspectives and trends

“…21,73 Conservative management has success rate of 75-80%. 1,21 In a review of 204 cases of chylothorax, hydrops was the single most important prognostic factor of a poor outcome in CC.…”

“…The mechanism of action of povidone-iodine appears to be related to enhanced sclerosis, 73 although the precise mode of action remains unclear. Iodine has strong oxidative and cytotoxic properties, which induces a potent inflammatory response in the wall of any fluid-containing structure.…”

“…Moreover, povidone-iodine may have anti-exudative properties related to the chelation of proteins. 73 However, frequent use of topical cutaneous povidone-iodine in neonates can induce allergic sensitization and impairment of thyroid function. 85 Chest pain, metabolic acidosis, hypotension, respiratory and renal failure have been previously observed in adult and pediatric patients who had received high doses of povidone-iodine topically applied in treatment of burns …”

Treatment of Posttransplant Lymphocele with Povidone-lodine Sclerosis: Long-Term Follow-Up

“…Thus, instillation volume, frequency of passes and duration of treatment vary ac cording to the author [6,[8][9][10][11], We use a standard instilla tion volume (50 ml) without taking into account the drained volume. Standardization of the method needs more series than those reported until now.…”

An Interesting Case of Failed Renal Transplant Complicated by a Lymphocele Infected with Pasteurella multocida and a Review of the Literature

“…Gilliard et al [52] report that 8 of 9 pre viously untreated lymphoceles were successfully treated with installation of 10% povidone iodine. Many other agents are reported in the literature: tetracycline; doxycycline; sodium tetradecylsulfate; sodium morrhuate; ampicillin, and fibrin [16,44,[53][54][55][56], The success of sclerosis in refractory lymphoceles does not appear to be as effec tive as in virgin lymphoceles. Pollack et al [46] treated six lymphoceles refractory to percutaneous drainage with tetracycline.…”