Cobalt–chromium–molybdenum (CoCrMo) alloys
are common
wear-exposed biomedical alloys and are manufactured in multiple ways,
increasingly using additive manufacturing processes such as laser
powder bed fusion (LPBF). Here, we investigate the effect of proteins
and the manufacturing process (wrought vs LPBF) and building orientation
(LPBF-XY and XZ) on the corrosion,
metal release, tribocorrosion, and surface oxide composition by means
of electrochemical, mechanical, microscopic, diffractive, and spectroscopic
methods. The study was conducted at pH 7.3 in 5 g/L NaCl and 5 mM
2-(N-morpholino) ethanesulfonic acid (MES) buffer,
which was found to be necessary to avoid metal phosphate and metal–protein
aggregate precipitation. The effect of 10 g/L bovine serum albumin
(BSA) and 2.5 g/L fibrinogen (Fbn) was studied. BSA and Fbn strongly
enhanced the release of Co, Cr, and Mo and slightly enhanced the corrosion
(still in the passive domain) for all CoCrMo alloys and most for LPBF-XZ, followed by LPBF-XY and the wrought
CoCrMo. BSA and Fbn, most pronounced when combined, significantly
decreased the coefficient of friction due to lubrication, the wear
track width and severity of the wear mechanism, and the tribocorrosion
for all alloys, with no clear effect of the manufacturing type. The
wear track area was significantly more oxidized than the area outside
of the wear track. In the reference solution without proteins, a strong
Mo oxidation in the wear track surface oxide was indicative of a pH
decrease and cell separation of the anodic and cathodic areas. This
effect was absent in the presence of the proteins.