of chemical energy to electric and/or mechanical energy, which is potentially profitable for various applications such as sensors, actuators, robots, switches, artificial muscles, and electricity generators. [22, Benefiting from the large available surface area, the unique electrical, thermal, and mechanical properties of graphene and/or its derivatives, as well as the ease of structure functionalization, device-oriented applications based on the interactions between graphene materials and water molecules have become of increasing concern. [61-66] However, no review has focused on the interactions between graphene/its derivatives and water molecules for actuation and electricity-generation applications so far. In this regard, we herein summarize the progress on moistureinduced deformable actuators and water-enabled electric generators achieved in recent years. The working mechanisms of actuators and electric generators will be introduced. The challenges and the potential trends in fabricating future devices on the basis of the effective interactions between graphene derivatives and water molecules are also discussed.The authors declare no conflict of interest.