PPARG modulation by bioactive compounds from Salvia officinalis and Glycyrrhiza glabra in type 2 diabetes management: A in silico study
Saeideh Hoseinpoor,
Jamshidkhan Chamani,
Mohammadreza Saberi
et al.
Abstract:This study delves into the exploration of bioactive constituents derived from Salvia officinalis and Glycyrrhiza glabra, with a focus on their potential to modulate peroxisome proliferator-activated receptor gamma (PPARG), a crucial regulator of glucose homeostasis and a key target for diabetes management. Through the rigorous application of in silico methodologies, the interactions between PPARG and six natural compounds, including kanzonol X, glabrol, linolenic acid, glycyrrhizin, carnosic acid, and licoflav… Show more
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