2016
DOI: 10.1016/j.bbalip.2016.09.010
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PPARγ regulates exocrine pancreas lipase

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Cited by 7 publications
(7 citation statements)
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“…Thus, it is possible to hypothesize that the increase of triglycerides excretion in feces caused by IHE could be due to its skill in reducing PPAR-γ expression and/or activity. In fact, as recently demonstrated, PPAR-γ transcriptionally up-regulates the gene expression of pancreatic triacylglycerol lipase [ 43 ].…”
Section: Resultsmentioning
confidence: 99%
See 1 more Smart Citation
“…Thus, it is possible to hypothesize that the increase of triglycerides excretion in feces caused by IHE could be due to its skill in reducing PPAR-γ expression and/or activity. In fact, as recently demonstrated, PPAR-γ transcriptionally up-regulates the gene expression of pancreatic triacylglycerol lipase [ 43 ].…”
Section: Resultsmentioning
confidence: 99%
“…Further, the high-fat diet containing 1% IHE feeding rats had shown a reduction in blood triglyceride levels coupled with an increase in their feces excretion [ 32 ]. Pancreatic triacylglycerol lipase is known to be the main enzyme involved in the hydrolysis of dietary triglycerides in adults [ 43 ]. However, data from different in vitro investigations about IAA inhibitory effect of pancreatic triacylglycerol lipase are contradictory [ 29 , 32 ].…”
Section: Resultsmentioning
confidence: 99%
“…In addition, PPAR‐γ can regulate pancreatic lipase, which is essential for hydrolyzing polyunsaturated fatty acids (PUFAs) …”
Section: Natural Ligands Of Ppar‐γ and Their Rolesmentioning
confidence: 99%
“…37 In addition, PPAR-γ can regulate pancreatic lipase, which is essential for hydrolyzing polyunsaturated fatty acids (PUFAs). 38 Benjamin et al have identified a class of LA, which is synthesized in the rumen of cattle and is termed as conjugated linoleic acid (CLA). The studies have revealed that CLA can inhibit colon carcinogenesis by enhancing PPAR-γ expression.…”
Section: Peroxisome Proliferator-activated Receptor γmentioning
confidence: 99%
“…Protein engineering purposes, especially in enzymes, is enlarging the active position, changes activity (change specific activity, change the characteristics of the substrate), sustainability (change thermal stability, protease stability and oxidation stability) and resistance to surfactants and detergents [14][15][16]. Schmidt and colleagues also used random mutation by errorprone, created a set of mutations for target enzyme to change anantio selectioiti [13].…”
Section: Introductionmentioning
confidence: 99%