Metal oxide nanoparticles, such as CuO and SnO 2 , are outstanding systems for H 2 S gas sensing in air. In this work, those nanoparticles were deposited with different mixing percentages on substrates to form percolating networks of nanoparticles. Electrical electrodes were deposited on the nanoparticles' films to investigate their gas sensing response against H 2 and H 2 S, and their electrical characteristics. The sensor devices based on CuO-SnO 2 nanoparticles revealed enhanced sensing characteristics against H 2 S with a sensitivity of 10 ppm. The enhanced sensing characteristics could be attributed to the formation of PN-junctions among CuO and SnO 2 nanoparticles. The reasonable production cost (due to simple structure and cheap used materials), low power consumption (~ 1 µW for H 2 S at room temperature), high sensitivity, high response, and reasonable response time of the present sensors qualify them for practical implementation in portable gas sensing devices with enhanced characteristics.