In many real-time kinematic (RTK) positioning applications, reference observations are transmitted over wireless links that can experience frequent interruptions or substantial delays. This results in large differential ages between base and rover observations, which, in turn, leads to a deterioration in positioning performance. To bridge the significant age difference, in this work, we propose a simple and effective scheme for modeling and compensating for such errors. Firstly, the overall differential age error was modeled using truncated Taylor expansion. Then, a time-differenced carrier phase (TDCP)-based observation model was established to estimate the errors with the Kalman framework. Since estimating the receiver’s clock error is unnecessary, equivalent transformation and sequential filtering technology were adopted to significantly reduce the computational complexity. Furthermore, a predictor performance monitor was introduced to mitigate the integrity risks that may occur due to model mismatches. The effectiveness of this scheme was validated by static and dynamic field experiments. The static experiment results showed that when the differential age was 60 s, the GPS and BDS satellites’ overall root mean square error (RMSE) with the asynchronous RTK (ARTK) prediction method was 2.8 and 5.5 times that of the proposed method, respectively. Moreover, when the differential age was 120 s, these values were 3.3 and 5.4 times that of the proposed method, respectively. The field experiment results showed that when the differential age was 60 s, the integer ambiguity fixed rate and false fixed rate of the ARTK method were 0.90 and 1.63 times that of the proposed method, respectively. Finally, at a 120 s differential age, these values were 0.78 and 4.78 times that of the proposed, respectively.