“…Although PCR systems based on AMELX/Y was occasionally applied to forensic samples as a stand alone system (Sullivan et al, 1993), the inclusion of the system in commercial kits (Holt et al, 2000) turned it into a worldwide used amplification system. Attempts were made on ancient human material (Faerman et al, 1995;Götherström et al, 1997;Hummel and Herrmann, 1991;Lassen et al, 2000;Stone et al, 1996), but as the contamination problem related to ancient human genetics made it impossible to validate the results (Kolman and Tuross, 2000;Malmström et al, 2005Malmström et al, , 2007Richards et al, 1995;Sampietro et al, 2006), it never became widely used in ancient DNA.…”