Practical Aspects of Insulin Pen Devices

Pearson, Teresa

doi:10.1177/193229681000400304

Cited by 90 publications

(84 citation statements)

References 51 publications

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“…20,36 While not confirmed in a clinical trial, a lower injection force is expected to facilitate simpler operation and reduced injection-site pain. 16,32,33,[37][38][39] JS had the lowest mean injection force of the HUPs investigated (5.94 N for the flow rate 6.00U/s). 22 All HUPs required a smaller mean injection force than the maximum force that can be exerted on such devices by the pediatric population (>21 N).…”

Section: Main Features and Technical Characterization Of Hupsmentioning

confidence: 99%

Half-Unit Insulin Pens: Disease Management in Patients With Diabetes Who Are Sensitive to Insulin

Klonoff

Nayberg

Stauder

et al. 2016

J Diabetes Sci Technol

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Background: Insulin pens represent a significant technological advancement in diabetes management. While the vast majority have been designed with 1U-dosing increments, improved accuracy and precision facilitated by half-unit increments may be particularly significant in specific patients who are sensitive to insulin. These include patients with low insulin requirements and in those requiring more precise dose adjustments, such as the pediatric patient population. This review summarized functional characteristics of insulin half-unit pens (HUPs) and their effect on user experience. Methods: The literature search was restricted to articles published in English between January 1, 2000, and January 1, 2015. A total of 17 publications met the set criteria and were included in the review. Results: Overall, studies outlined characteristics for 4 insulin HUPs. Based on their functionality, the pens were generally similar and all met the ISO 11608-1 criteria for accuracy. However, some had specific advantageous features in terms of size, weight, design, dialing torque, and injection force. Although limited, the currently available user preference studies in children and adolescents with diabetes and their carers suggest that the selection of an HUP is likely to be influenced by a combination of factors such as these, in addition to the prescribed insulin and dosing regimen. Conclusions: Insulin HUPs are likely to be a key diabetes management tool for patients who are sensitive to insulin; specific pen features may further advance diabetes management in these populations.

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Section: Main Features and Technical Characterization Of Hupsmentioning

confidence: 99%

Half-Unit Insulin Pens: Disease Management in Patients With Diabetes Who Are Sensitive to Insulin

Klonoff

Nayberg

Stauder

et al. 2016

J Diabetes Sci Technol

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“…Bu nedenle hastaların insülin kullanımıyla ilgili eğitilmesi gerekmektedir (5 Hastanede yatan Tip 2 Diyabet hastalarında tek kullanımlık insülin kalemi kullanımının değerlendirildiği çalışmamızın sonuçlarına dayanarak, hastaların tek kullanımlık insülin kalemi kullanımı ile ilgili bilgilerinin artırılmasına ve tutumlarının iyileştirilmesine gereksinim olduğu gözlenmiştir. Literatürde örnekleri görüldüğü gibi sadece ülkemize özgü olmayan bu sorunların aşılmasında eczacılara da önemli görevler düşmektedir.…”

Section: Tartişma Ve Sonuçunclassified

Tip 2 Diyabet Hastalarının Tek Kullanımlık İnsülin Kalemi Kullanımı ile İlgili Bilgi ve Tutumlarının Değerlendirilmesi

Okuyan¹

2014

mpj

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GİRİŞİnsülin kalemi kullanımının daha kolay, daha kullanışlı ve şırıngaya göre daha az acılı olduğu, hastalar tarafından daha yüksek oranda tercih edildiği ve kabul edildiği kanıtlanmıştır (1). Ayrıca yapılan çalışmalarda, insülinin şırınga ile kullanımının aksine insülin kaleminin hastalarda uyuncu artırdığı belirlenmiştir (2, 3). Kapsamlı bir retrospektif çalışma sonucuna göre, insülin aspart kalemi kullanımının geleneksel şırınga yöntemine göre hastalarda daha az hipoglisemik olayla sonuçlandığı ve diyabete bağlı komplikasyon maliyetinin daha düşük olduğu görülmüştür (4). Görme bozukluğu olan veya el becerisi azalmış olan hastalarda insülin şırıngalarının yerine, kullanım kolaylığı nedeniyle insülin kalemlerinin daha uygun ve faydalı olduğu belirtilmiştir (5).

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“…15 Studies and reviews of technical qualities of insulin pens commonly claim theoretical usefulness to people with dexterity or visual disabilities. 4,5,7,[16][17][18][19][20][21][22] Future studies making such claims should clarify the significance by linking laboratory data to information about the relevant human factors. Furthermore, studies of diabetes technology that include human subjects should purposefully include individuals who have a full range of severity of the impairments for which benefit is claimed.…”

Section: In This Issue Of Journal Of Diabetes Science and Technologymentioning

confidence: 99%

Analysis: Linking Laboratory Data to Human Factors and Inclusion of Persons with Disabilities in Diabetes Technology Research

Williams

2011

J Diabetes Sci Technol

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In this issue of Journal of Diabetes Science and Technology, Friedrichs and colleagues present a study of the injection force of four reusable insulin pens and another study of the dosing accuracy of three different insulin pens. For the study of injection force, the authors claim that lower injection force has numerous advantages for patients, including making use of pens easier for people with decreased hand strength. For the study of dosing accuracy, the authors state that dose accuracy is critical for glycemic control.Both study designs have significant strengths, including measurements of the variable of interest using two different methodologies and thorough documentation of methods and materials. However, the careful, precise measurements of injection force and dosing accuracy are not matched by equivalent precision supporting the significance of the studies. The authors do not provide any information about what measured injection force is easy or difficult for individuals with and without manual problems or what level of dosing inaccuracy is clinically significant. Therefore, the implications for practice remain unclear. Data about these and other relevant human factors are needed to provide meaningful context for laboratory measurements of diabetes technologies. Furthermore, researchers conducting studies of diabetes technology that include human subjects should intentionally recruit persons with disabilities so diabetes care professionals can know whether and how technical information about diabetes technology applies to the full range of patients, including those with disabilities.

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Practical Aspects of Insulin Pen Devices

Cited by 90 publications

References 51 publications

Half-Unit Insulin Pens: Disease Management in Patients With Diabetes Who Are Sensitive to Insulin

Half-Unit Insulin Pens: Disease Management in Patients With Diabetes Who Are Sensitive to Insulin

Tip 2 Diyabet Hastalarının Tek Kullanımlık İnsülin Kalemi Kullanımı ile İlgili Bilgi ve Tutumlarının Değerlendirilmesi

Analysis: Linking Laboratory Data to Human Factors and Inclusion of Persons with Disabilities in Diabetes Technology Research

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