“…At the moment, several European countries such as Belgium [2], France [3], Germany [4], Sweden [5], as well as Australia [6] and several US states [7] have adopted an analytical or 'per se' legislation to address this problem. In Belgium, a driver is sanctioned if D 9 -tetrahydrocannabinol (THC), cocaine or its metabolite benzoylecgonine, morphine, amphetamine, 3,4-methylenedioxy-N-methylamphetamine (MDMA), 3,4-methylenedioxy-N-ethyl-amphetamine (MDEA) or N-methyl-1-(3,4-methylenedioxy-phenyl)-2-butanamine (MBDB) are detected in plasma in concentrations higher than the cut-off values mentioned in the law [2].…”