Practical Aspects of the Postthrombotic Syndrome

Puggioni, Alessandra; Kalra, Manju; Gloviczki, Péter

doi:10.1016/j.disamonth.2005.03.012

Cited by 5 publications

(2 citation statements)

References 34 publications

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“…If a person suffers a recurrent thrombosis the incidence of this syndrome increases six fold. [6][7][8] A PTS, most frequently characterized by swelling, rarely by ulceration, occurs 30-50% of the time following an episode of DVT and may not appear for 2-10 years after the initial thrombotic event. We know that the use of appropriate compression stockings of at least 20-30 mm Hg and preferably 30 40 mm Hg pressure decreases the incidence of the postthrombotic syndrome by 50% during the first 2 years after the thrombosis.…”

Section: How Do Venous Ulcers Develop?mentioning

confidence: 99%

Venous Ulcers

Caprini

Partsch

Simman

2012

Journal of the American College of Clinical Wound Specialists

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Venous leg ulcers are the most frequent form of wounds seen in patients. This article presents an overview on some practical aspects concerning diagnosis, differential diagnosis and treatment. Duplex ultrasound investigations are essential to ascertain the diagnosis of the underlying venous pathology and to treat venous refluxes. Differential diagnosis includes mainly other vascular lesions (arterial, microcirculatory causes), hematologic and metabolic diseases, trauma, infection, malignancies. Patients with superficial venous incompetence may benefit from endovenous or surgical reflux abolition diagnosed by Duplex ultrasound. The most important basic component of the management is compression therapy, for which we prefer materials with low elasticity applied with high initial pressure (short-stretch bandages and Velcro-strap devices). Local treatment should be simple, absorbing and not sticky dressings keeping adequate moisture balance after debridement of necrotic tissue and biofilms are preferred. After the ulcer is healed compression therapy should be continued in order to prevent recurrence.

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Section: How Do Venous Ulcers Develop?mentioning

confidence: 99%

Venous Ulcers

Caprini

Partsch

Simman

2012

Journal of the American College of Clinical Wound Specialists

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“…Surgery-related expenses and the treatment of open ulcers in patients with severe PTS were both significant cost drivers.Heit et al21 investigated the incidence of venous stasis syndrome (VSS), another term for PTS, and of venous ulcer a condition commonly associated with or resulting from PTS, in a community population during the period 1966-90. According to data published in 2005, the estimated U.S. incidence of VSS was about 150,000 new cases per year, with approximately 25% of those cases attributable to PTS 22. The work of Heit et al indicated that the aggregate impact of the two disorders on annual U.S. health care costs was conservatively estimated at $200 million annually (in 1990 U.S. dollars).…”

mentioning

confidence: 96%

Quality of life and economic costs associated with postthrombotic syndrome

Kachroo¹,

Boyd²,

Bookhart

et al. 2012

American Journal of Health-System Pharmacy

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Appropriate measures to decrease PTS-related burdens may include the prevention of DVT, clear diagnostic criteria for PTS, and an education campaign aimed at increased standardization in the management of DVT. Gaps in the current understanding of the risk factors, diagnostic criteria, preventive strategies, and even treatment modalities for PTS hamper the ability of clinicians to employ measures that could reduce the occurrence of this disorder and the associated morbidity.

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Venous Thromboembolism

Kim¹,

Bartholomew²

2009

Antithrombotic Drug Therapy in Cardiovascular Disease

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Practical Aspects of the Postthrombotic Syndrome

Cited by 5 publications

References 34 publications

Venous Ulcers

Venous Ulcers

Quality of life and economic costs associated with postthrombotic syndrome

Venous Thromboembolism

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