Practical Drug Evaluation Method

Ainslie, John D.

doi:10.1001/archpsyc.1965.01720340040006

Search citation statements

Order By: Relevance

Paper Sections

Select...

Discussion1

Citation Types

Supporting

Mentioning

Contrasting

Year Published

1966

1982

Publication Types

Select...

Article6

Relationship

Self Cite0

Independent6

Authors

Journals

Cited by 11 publications

(1 citation statement)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Unfortunately, the time period necessary for maximum active drugplacebo response differences is unknown. Ainslie et al (1965) reported imipramine-placebo response differences which appeared to be increasing at week 6. In a much longer trial (DiMascio et al 1979) the main effects for pharmacotherapy reflected by HRS ratings were greatest at week 16.…”

Section: Discussionmentioning

confidence: 97%

Early improvement as a predictor of response to amitriptyline and nortriptyline: a comparison of 2 patient samples

et al. 1982

View full text Add to dashboard Cite

SynopsisThis study compared serial severity ratings from 2 methodologically similar tricyclic antidepressant studies. Though the groups resembled each other in terms of diagnosis and baseline severity, response patterns were surprisingly different. In particular, early change was highly predictive of outcome in one group but not in the other. The results of response predictor studies must, therefore, be generalized with caution. These data, nevertheless, do allow some guidelines for predicting response from early changes and severity.

show abstract

Section: Discussionmentioning

confidence: 97%