Practical Flow Cytometry in Haematology Diagnosis

Abstract

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Hematogones in the Peripheral Blood of a 5½-Month-Old Boy with Cyclic Neutropenia Due to Heterozygous, Novel ELANE Gene Mutation p.Q97P, c.290 A>C

“…A decreased number of hematogones is noted in myelodysplasia, bone marrow hypoplasia, and bone marrow infiltrations. The number of hematogones essentially reflects the degree of potential bone marrow reserve [7]. Early hematogones resemble lymphoblasts morphologically.…”

“…2). In the normal bone marrow, stage 2 hematogones comprise about 75% of all hematogones, whereas stage 1 and stage 3 each comprise about 13% of all hematogones [7]. In the recovering marrows (eg, postchemotherapy or after viral infection), there are more stage-1 hematogones, left shifted [7].…”

Parallel evaluation of cell‑based phage display panning strategies: Optimized selection and depletion steps result in AML blast‑binding consensus antibodies

“…Binding activity was scored positive (+), if at least 10% of the cell population ( 25 ) were confirmed positive and if an increase in median fluorescence intensity of at least 75% was detectable compared to the fluorescence signal of the control (unselected, naïve Tomlinson J library).…”

Assessment of the activation ability of lymphocytes associated with local injections of acidic peptodoglycan in patients with acne

“…CD69 формирует димеры, которые действуют как передатчики сигналов, усиливая ак-тивацию других клеток. Этот белок экспрессируется в больших количествах на T-лимфоцитах, выделен-ных из воспалительных инфильтратов при ряде хро-нических заболеваний аутоиммунной природы [6,[13][14][15].…”