Practical Means of Preoperative Diagnostics of Primary Fallopian Tube Cancer

Sumtsov, Dmytro Heorhiiovych; Гладчук, І. З.; Kashtalian, N.; Sumtsov, Georgiy O.

doi:10.36740/wlek202102120

Cited by 7 publications

(4 citation statements)

References 26 publications

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“…The use of FDG-PET/CT (fluorodeoxyglucose-positron emission tomography/computed tomography) has been tested in the search and evaluation of incomplete tumor removal; however, the data to date cannot support the examination as a routine diagnostic examination in daily clinical practice [ 25 ]. A recent study suggests that complex examination, including cytological examination of abnormal vaginal discharge, tumor markers, computed tomography, magnetic resonance imaging, PET-CT, and laparoscopy, may significantly help in the diagnosis and to avoid inadequate surgery [ 26 ].…”

Section: Discussionmentioning

confidence: 99%

Primary Fallopian Tube Carcinoma: An Extremely Rare Gynecological Cancer Misdiagnosed Intraoperatively as Benign Ovarian Neoplasm: A Case Report

Thanasa

Stamouli

Gerokostas

et al. 2022

Clinics and Practice

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Primary fallopian tube carcinoma is very rare. Diagnosis is challenging. The description of our case concerns an asymptomatic 71-year-old patient who came for a routine gynecological examination. Imaging of the pelvis revealed the presence of a two-chambered cystic formation in the anatomical position of the right ovary. It was decided to investigate the disease by laparotomy. Examination of the frozen section from the site of the cystic lesion was negative for malignancy. An abdominal total hysterectomy was performed with bilateral salpingo-oophorectomy. Serous carcinoma of the fallopian tube was diagnosed postoperatively by histological examination of the surgical preparation. Immediately after surgery, the patient’s health was good.The patient was referred to an oncology center and was monitored. Chemotherapy based on platinum and taxane was recommended. Six months after the operation the patient is in good health. The possibility of a second surgery to treat fallopian tube cancer with pelvic lymph node dissectionis under discussion and is expected to be decided by oncologists and gynecologists-oncologists. In this article, after describing the case report, a brief review of this rare entity disease’s diagnostic and therapeutic approach is attempted.

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Section: Discussionmentioning

confidence: 99%

Primary Fallopian Tube Carcinoma: An Extremely Rare Gynecological Cancer Misdiagnosed Intraoperatively as Benign Ovarian Neoplasm: A Case Report

Thanasa

Stamouli

Gerokostas

et al. 2022

Clinics and Practice

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“…Approximately 70% of patients with PFTC have pelvic inflammatory disease, and 49% complain of infertility according to the patients’ history and intraoperation revision data. 7 The incidence rate of PFTC is 0.36 to 0.41/100,000 women each year. However, from 2001 to 2014, the incidence of PFTC increased 4.19 fold.…”

Section: Discussionmentioning

confidence: 99%

18-F fluorodeoxyglucose positron emission tomography/computed tomography findings of bilateral primary fallopian tube carcinoma and metastasis to the uterus: a case report and literature review

et al. 2022

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Existing literature on primary carcinoma of the fallopian tube is limited because of the rarity of this disease. We report a patient with intermittent vaginal bleeding and vaginal discharge who underwent transvaginal ultrasound, magnetic resonance imaging, and 18-F-fluorodeoxyglucose positron emission tomography/computed tomography (18-F FDG PET/CT) in our hospital. Ultrasound showed a bilateral fallopian tube mass and a uterine lesion. Magnetic resonance imaging revealed typical sausage-shaped bilateral adnexal masses, but overlooked a small lesion in the uterus in the initial diagnosis. FDG PET/CT findings not only showed bilateral fallopian tube masses and uterine lesions, but also ruled out distant metastasis. Postoperative pathology confirmed bilateral primary high-grade serous adenocarcinoma of the fallopian tube with implants in the uterus. These findings suggest that 18-F FDG PET/CT imaging could be a good approach for the diagnosis and staging of primary carcinoma of the fallopian tube.

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“…A typical feature of FTC is the correlation between pain and discharge: increased pathological discharge after an episode of pain. Bimanually, at the time of consulting a gynecologist, 70 to 76% of patients already present with anatomical changes in the internal genital organs, mainly the uterine adnexa, which is often a sign of an old disease [1,20].…”

Section: Causes Of Ftcmentioning

confidence: 99%

“…The errors were probably caused by the lack of the following: developed laparoscopic semiotics of FTC, proper examination of the longitudinal section of the removed fallopian tube in the operating room, and suboperative morphological diagnosis. Despite the complexity of preoperative diagnosis of FTC, clinical manifestations and comprehensive use of additional modern examination methods make it possible to avoid mistakes in most cases [20,21,32,37].…”

Section: Problems and Capabilities Of Ftc Diagnosismentioning

confidence: 99%

Primary Fallopian Tube Cancer: A Literature Review

Sumtsov

2023

EUMJ

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This literature review presents an analysis of diagnostic methods and treatment of a relatively rare and highly malignant tumor – primary fallopian tube cancer, which is poorly studied and difficult to diagnose. The study of the fallopian tube disorder is very relevant, as the fallopian tube mucosa can be a source of "serous carcinogenesis" for serous ovarian and peritoneal cancer. The author selected more than 50 scientific works from the world literature on the problems of incidence, diagnosis, and treatment of primary fallopian tube cancer and conducted a detailed analysis of them. The author draws attention to the risk group for primary fallopian tube cancer. Women with BRCA-1 and BRCA-2 mutations are more likely to develop FTC, especially in families with a history of breast and (or) ovarian cancer. Approximately 30% of women with FTC have a BRCA-1 or BRCA‑2 mutation. All patients with a burdened history and pathologic mutations should be considered candidates for routine rehabilitation. The author analyzes options for improving preoperative diagnosis using modern methods of additional examination, such as tumor markers, vacuum suction biopsy, transvaginal ultrasound, CT and MRI, and diagnostic laparoscopy. The author emphasizes that it is possible to avoid diagnostic errors during operations using a detailed examination of the affected fallopian tube mucosa on a longitudinal section and suboperative methods of morphological diagnosis. In addition, the author points out the prognostic importance of adequate staging and complete courses of adjuvant polychemotherapy according to modern clinical protocols. The author also draws attention to the interdependence of prevention methods, diagnosis, and treatment of FTC and ovarian cancer.

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Practical Means of Preoperative Diagnostics of Primary Fallopian Tube Cancer

Cited by 7 publications

References 26 publications

Primary Fallopian Tube Carcinoma: An Extremely Rare Gynecological Cancer Misdiagnosed Intraoperatively as Benign Ovarian Neoplasm: A Case Report

Primary Fallopian Tube Carcinoma: An Extremely Rare Gynecological Cancer Misdiagnosed Intraoperatively as Benign Ovarian Neoplasm: A Case Report

18-F fluorodeoxyglucose positron emission tomography/computed tomography findings of bilateral primary fallopian tube carcinoma and metastasis to the uterus: a case report and literature review

Primary Fallopian Tube Cancer: A Literature Review

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