An active duty male presented to the emergency room with dyspnea for 2 days after undergoing liposuction surgery. Upon presentation, the patient was afebrile, tachycardic, tachypneic, and hypoxemic. The initial chest radiograph demonstrated bilateral patchy opacities and the PaO 2 /FiO 2 ratio was Ͻ200. The patient was admitted to the medical intensive care unit for supportive care. He was treated empirically for pneumonia. Blood and sputum cultures were negative. A computed tomography angiogram of the chest was negative for pulmonary embolism but did reveal a bilateral, perihilar air space process. The patient's oxygen requirement improved and the abnormal chest radiographic findings resolved over the next 48 hours. Given his clinical presentation, negative workup, and rapid recovery, the patient was given a presumptive diagnosis of pulmonary fat embolism. Fat embolism occurs when adipocytes and small blood vessels are damaged during the liposuction procedure. Patients may present with low-grade fever, tachycardia, tachypnea, hypoxemia, and hypocapnia. The differential diagnosis includes venous thromboembolism, aspiration pneumonitis, and pneumonia. The mainstay of treatment for pulmonary fat embolism is supportive care. The risk of mortality is 5 to 15%.
Case ReportA 31-year-old African-American male with no major medical problems except sickle cell trait presented to the emergency room (ER) with shortness of breath for 2 days' duration after having undergone liposuction surgery. He also complained of a cough productive of clear sputum, but he denied experiencing fevers, chills, diaphoresis, hemoptysis, rash, confusion, sick contacts, or recent travel. He also denied any anginal or pleuritic chest pain.The patient underwent liposuction for the removal of "love handles." The procedure was performed at an outpatient surgical center, lasted several hours, and involved the use of general anesthesia, but the perioperative records were not available. The patient's dyspnea began immediately after the surgery. He reported wearing compression stockings perioperatively and postoperatively, but denied being treated with any anticoagulants such as heparin or enoxaparin.The patient was discharged to his home on the day of surgery without any specific treatment for his dyspnea. On postoperative day 1, he returned to the surgical center where he was seen by the plastic surgeon, who prescribed prednisone, reportedly for upper airway edema following the recent intubation. Again, the patient was discharged home, but his dyspnea became progressively worse, such that he sought attention in the ER on postoperative day 2.The patient's past medical history was notable for sickle cell trait. His surgical history was notable only for the recent liposuction. He had no known drug allergies. His current medications included cephalexin, acetaminophen/hydrocodone, and prochlorperazine, which were prescribed after the surgery. The patient's family history was notable for a mother with sickle cell disease. He denied cigarette smoking, alcoho...