Continuous palliative sedation (CPS) is a treatment aimed to relieve refractory symptom in end-of-life patient. The decision to start it involves palliative care unit, patient and caregiver (CG). The objective of this study was to evaluate the feasibility of an instrument to monitor CPS in end-of-life patients. This prospective study was conducted for one year at Bentivoglio Hospice (Bologna, Italy). The multiprofessional medical record (MPMR) is compiled every time a patient begins the CPS. It was composed by four categories of questions on the patient, CG, clinical and pharmacological aspects. MPMR were compiled for 91(16.9%) patients among the 538 patients who died during the study period. Eighty-nine patients had cancer while two had non-neoplastic disease. The most common refractory symptom was dyspnea (58.2%) followed by delirium (36.3%). Before the onset of the refractory symptom, we openly discussed sedation with 13 patients, while direct patient's agreement to start palliative sedation was possible in 16 cases only. The hospice team evaluated the experience of CPS for CGs. Midazolam was the sedative drug preferred for induction and maintenance of CPS and 64.8% of patients did not need dosage increases during the maintenance period. A careful evaluation of CPS is important in clinical and pharmacological aspects and in the decision-making process shared by the care team, patient and CG. The MPMR is easy to compile, improves evaluation and follow-up of CPS. It also promotes standard team language and allows a comparison with other settings. of the case). We noticed that there is a lack of data in the clinical diary about CPS. For example the steps for the diagnosis of the refractory symptom weren't recorded, the specific treatments administered to control the symptom before the beginning of the CPS, were not always reported in the clinical diary but always in pharmacology report. The RASS scale and the discussion about CPS between palliative care team and the patient were never reported. At the aim of filling this lack we proposed and verified a tool that permitted to report the decision making process of the CPS, simple to use.
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MethodsThis is a feasibility pilot study conducted for 12 months at Bentivoglio Hospice (Bologna, Italy). During the study period, every patient admitted to our Hospice was evaluated for enrollment. Inclusion criteria were as follows: a) age>18years, b) inpatient hospice, c) affected by neoplastic or not neoplastic disease, d) onset of a refractory symptom. Exclusion criteria were as follows: a) age<18 years, b) a challenging symptom. We develop a multi-professional medical record (MPMR) focusing on the multiple aspects of the CPS: the patients, the caregivers' experience, and the pharmacological aspects of the sedation process as tool for the assessment and follow up of CPS. The MPMR is an ad hoc clinical chart within medical record for monitoring the different aspects of CPS in end-of-life patients with neoplastic or other diseases admitted to the Hospice, who s...