This article concludes the special issue on Biosemiotic Entropy looking toward the future on the basis of current and prior results. It highlights certain aspects of the series, concerning factors that damage and degenerate biosignaling systems. As in ordinary linguistic discourse, well-formedness (coherence) in biological signaling systems depends on valid representations correctly construed: a series of proofs are presented and generalized to all meaningful sign systems. The proofs show why infants must (as empirical evidence shows they do) proceed through a strict sequence of formal steps in acquiring any language. Classical and contemporary conceptions of entropy and information are deployed showing why factors that interfere with coherence in biological signaling systems are necessary and sufficient causes of disorders, diseases, and mortality. Known sources of such formal degeneracy in living organisms (here termed, biosemiotic entropy) include: (a) toxicants, (b) pathogens; (c) excessive exposures to radiant energy and/or sufficiently powerful electromagnetic fields; (d) traumatic injuries; and (e) interactions between the foregoing factors. Just as Jaynes proved that irreversible changes invariably increase entropy, the theory of true narrative representations (TNR theory) demonstrates that factors disrupting the well-formedness (coherence) of valid representations, all else being held equal, must increase biosemiotic entropy-the kind impacting biosignaling systems.Keywords: agreement condensation; biological signaling systems; biocontrol systems; biosemiotic entropy; Bose-Einstein condensation; cancers; encephalopathies; fit-get-rich network theory; information theory; pathogens; pragmatic information; synergistic effects; true narrative representations (TNRs)OPEN ACCESS Entropy 2014, 16 4061
Background and Introduction to the Central ThesisThis is the closing entry for the special issue on Biosemiotic Entropy [1]. It looks toward the future on the basis of theory and known factors that tend to increase biosemiotic entropy by disrupting biosignaling systems. This twelfth paper of the series highlights critical definitions and explains the theory serving as a ground for the preceding papers and certain spin-offs. It points to salient empirical findings, and gives a telescopic abstract rather than a detailed summary of the entries. Interested readers can get more details from published abstracts and from the entire articles of the series that are all freely accessible. Each one was written and published as if it were an independent contribution to the general stream under the Entropy banner though each paper is plainly marked as an item in the special issue on Biosemiotic Entropy. Also, each one addressed the special problem posed for the series: contributors were asked for an argument (preferably with experimental evidence) "pro, con, or offering any alternative to the idea that corrupted biological messages account for (but, of course, are not limited to) anaphylaxis, preeclampsia, sudden deat...