Prangos platychlaena: State of the Art from Ethnopharmacology, Phytochemical, Toxicological and Pharmacological Perspective

Abstract

The Mediterranean region is a rich source of bioactive phytochemicals contained in plants and the secret of longevity. Mediterranean region represents an intangible cultural heritage of humanity and it is partially still based upon many wild plants. The use of wild plants possibly emerged in the Neolithic period in the Fertile Crescent and migrated westwards through the Mediterranean area. The genus of Prangos has 30 species distributed from the Mediterranean to central Asia, 14 of them are found in Turkey while 7 of them are found in the different areas of the Kurdistan region of Iraq. Prangos platychlaena Boiss. (family: Apiaceae) abundantly found in the mountains of Halgurd. P. platychlaena has been reported as potent antioxidant plant, and traditionally used as carminative, and diuretic. Prangos also traditionally used in the treatment of burning and wounds, kidney, and urinary disorders. P. platychlaena have been reported to cause toxicological effects in animals, and shows potential cytotoxic activities in invitro studies. The current review has covered comprehensively habitats, ethnopharmacology, phytochemistry, toxicological and pharmacological actions of P. platychlaena.