“…Owing to a systemic overestimation by TTE, higher cut-off values of LAA blood flow velocities were found, with an acceptable predictive accuracy for the validated TEE values. In the clinical setting, the identification of low (<20 cm/s) or high (>40 cm/s) LAA flow velocity at TEE reliably indicates a high and low risk status for embolic events, guiding antithrombotic or anticoagulation strategies before the cardioversion procedure [17] and one year postoperatively [18]. In the SPAF-III trial [19], in a large population of 721 patients with non-valvular atrial fibrillation, a LAA emptying flow velocity of <20 cm/s at TEE identified patients at higher risk of LAA spontaneous echo contrast, thrombi and cardioembolic stroke.…”