Pre‐ and postnatal findings in a boy with duplication of the bladder and intestine: Report and review

Abstract

We describe a boy with a septated bladder and dilated bowel loop found on prenatal ultrasonography. Subsequent prenatal MRI diagnosed a probable caudal duplication anomaly. Postnatal investigations and surgical findings confirmed duplication of bladder, urethra, and bowel from distal ileum to rectum. This is the first reported case of combined bladder and colon duplication suspected antenatally with thorough imaging investigations including fetal MRI. While diagnosis of bladder duplication has been described, prenatal diagnosis of intestinal duplication has not been documented previously. This report of prenatal imaging with surgical and pathological correlation contributes to our detailed understanding of the spectrum of anatomy seen in caudal duplication anomaly.

Novel mosaic SRY gene deletions in three newborn males with variable genitourinary malformations

“…Patient 1, in our study, had a duplication of the colon and anus, a dysmorphic sacrum, and lumbar scoliosis, along with hypospadias and ambiguous genitalia. Variable combinations of duplications and anomalies involving structures within the gastrointestinal and genitourinary systems, as well as the vertebral column, have been described in patients with caudal duplication (Alfadhel et al, ). Although hypospadias was reported in one individual with caudal duplication involving a duplication of the penis (Bannykh et al, ), neither hypospadias nor ambiguous genitalia are common features of caudal duplication.…”

Concomitant urethral triplication, bladder, and colon duplication

“…The duplication could be incomplete when the bladder is divided into two compartments by a coronal or sagittal septum with a single urethra or complete by the termination of both bladders to separate urethras [2]. In present case, the bladder is divided into two parts by a complete sagittal septum, and each part has its own separate urethra in complete duplication of bladder, caudal duplication should be assessed [3].…”

“…Some cases of caudal duplication presents with pyelonephritis, intestinal and urinary tract obstruction. Others remain asymptomatic and discovered incidentally [2]. The alimentary tract duplication is more common in pediatric ages.…”

“…Bladder duplication is also a very rare entity that can be complete or incomplete. In incomplete duplication of the bladder, the anomalies of the caudal structures (including colon) should be assessed [2]. Caudal duplication is a very rare entity that is defined as the duplication of various parts of the caudal region (such as bladder, urethra, colon, rectum, and anal canal).…”

“…Colonic duplication represents 4-18 percent of alimentary tract duplications. This anomaly is usually asymptomatic, but when symptomatic, it presents with constipation, bleeding, or manifestations of obstruction and malignancy [2,3]. The authors present the first case of urethral triplication associated with bladder, sigmoid, and rectum duplication whose main clinical manifestation was fecaluria and recurrent urinary tract infection.…”