Pre-Anesthetic Medications in Patients Undergoing Exploratory Laparotomy: Results of a Cross-Sectional Study

Abstract

Objective: The objective of this study was to understand the pattern of pre-anesthetic medication utilization in patients undergoing exploratory laparotomy. Methods:In this cross-sectional study, we reviewed the records of patients who underwent exploratory laparotomy under general anesthesia. Descriptive data of the pre-anesthetic medications used in the patients are presented. Results:A total of 49 patients with mean ± SD age of 65.85±34.15 years were included in the study. The study population was dominated by male patients (65.85%). Two major indications for exploratory laparotomy in the study population were perforation peritonitis 19 (38.77%) and intestinal obstruction 9 (18.37%). Ondansetron was used in all patients. Metoclopramide and ranitidine were used in 48 (98%) patients each. Midazolam was given to 43 (87.8%) patients. A total of 41 (83.7%) patients received anticholinergic agent glycopyrrolate or atropine. Pentazocine and fentanyl were used in 39 (79.6%) and 10 (20.4%) patients, respectively. Conclusion:Ondansetron, metoclopramide, ranitidine, midazolam, glycopyrrolate, and pentazocine were the major pre-anesthetic medications in patients undergoing exploratory laparotomy. Glycopyrrolate was the most preferred anticholinergic agent.

Utilization of Pre-Anesthetic Medications for Major Surgical Procedures at a Tertiary Care Center: A Descriptive Cross-sectional Study

“…Among the pre-anesthetic medication, the benzodiazepine group of the drug was highly prescribed drugs. 30 In our study Midazolam was commonly utilized drugs similar to finding Sheen MJ, et al 31 study whereas these findings differ from the studies of Patil A, 32 Biswas P, et al 30 where the most commonly used anxiolytic was alprazolam. Here the glycopyrrolate 352 (88%) has been utilized which were more potent than atropine, used routinely as a pre-medication purpose and have less risk to the cardiovascular system, better control of oropharyngeal secretions during reversal stage 8 when compared to Zeev N and Mirakur RK, et al where atropine was the most commonly used.…”