2013
DOI: 10.1002/14651858.cd010241.pub2
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Pre-operative endometrial thinning agents before endometrial destruction for heavy menstrual bleeding

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Cited by 42 publications
(8 citation statements)
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“…37 Indeed, this corroborates the findings of a 2013 Cochrane review assessing preoperative endometrial thinning with a GnRH agonist, danazol, progestin–estrogen combinations, and progestogens, which confirmed that, although both the GnRH agonist and danazol were effective, GnRH agonist therapy seemed to be better tolerated. 38…”
Section: Discussionmentioning
confidence: 99%
“…37 Indeed, this corroborates the findings of a 2013 Cochrane review assessing preoperative endometrial thinning with a GnRH agonist, danazol, progestin–estrogen combinations, and progestogens, which confirmed that, although both the GnRH agonist and danazol were effective, GnRH agonist therapy seemed to be better tolerated. 38…”
Section: Discussionmentioning
confidence: 99%
“…Endometrial thinning prior to hysteroscopic surgery leads to a clearer view, which reduces the risk of intraoperative complications such as perforation, and leads to a shorter operation time in general. Furthermore, a thin endometrium improves the intra-uterine operating environment, and reduces distension medium absorption ( Sowter et al, 2002 ; Tan et al, 2013 ). This may also result in a greater improvement in long term outcomes such as menstrual loss and dysmenorrhoea.…”
Section: Discussionmentioning
confidence: 99%
“…However, there is no consensus on the optimal method of endometrial preparation (GnRH-a, Danazol, or the combined oral contraceptive) and whether these agents have any benefits for second-generation endometrial ablation, or other hysteroscopic surgery such as removal of septae or submucous fibroids [9]. GnRH analogues are very potent drugs, producing menopausal symptom side effects.…”
Section: Patient Preparationmentioning
confidence: 99%