Pre-operative prediction of post–VAD implant mortality using easily accessible clinical parameters

Klotz, Stefan; Vahlhaus, Christian; Riehl, C.; Reitz, Christiane; Sindermann, Juergen R.; Scheld, Hans H.

doi:10.1016/j.healun.2009.06.008

Cited by 52 publications

(51 citation statements)

References 24 publications

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“…17 Therefore, we performed a subset analysis for the patients within the INTERMACS level 1 group treated with or without preoperative ECMO support. Figure 4 shows the cumulative survival rates of patients in the INTERMACS level 1 group categorized according to renal function level and preoperative ECMO requirement.…”

Section: Resultsmentioning

confidence: 99%

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Predictor of Early Mortality for Severe Heart Failure Patients With Left Ventricular Assist Device Implantation

Yoshioka

Sakaguchi

Saito

et al. 2012

Circ J

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Section: Resultsmentioning

confidence: 99%

“…17 As shown in Figure 4, the cumulative survival curve mainly depends on the existence of renal dysfunction rather than on ECMO support. According to Lietz et al, the risk of LVAD surgery was not correlated with the hemodynamic severity of heart failure but was correlated with the presence of comorbidities.…”

Section: Discussionmentioning

confidence: 98%

Predictor of Early Mortality for Severe Heart Failure Patients With Left Ventricular Assist Device Implantation

Yoshioka

Sakaguchi

Saito

et al. 2012

Circ J

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“…Others have also reported preoperative mechanical ventilation as a risk factor for death while on support. 16 Indeed, the need for preoperative mechanical ventilation reflects the magnitude of cardiogenic shock and the patient's critical preoperative condition.…”

Section: Survival After Transplantationmentioning

confidence: 99%

Experience with the SynCardia total artificial heart in a Canadian centre

Nguyen

Pellerin

Perrault

et al. 2017

CJS

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Background:The SynCardia total artificial heart (TAH) provides complete circulatory support by replacing both native ventricles. Accepted indications include bridge to transplantation and destination therapy. We review our experience with TAH implantation during a period when axial flow pump became available. Methods:We retrospectively analyzed the demographics, clinical characteristics and survival of all patients receiving the TAH. Results:From September 2004 to November 2016, 13 patients (12 men, mean age 45 ± 13 yr) received the TAH for refractory cardiogenic shock secondary to idiopathic (56%) or ischemic (17%) cardiomyopathy and to other various causes (33%). Before implantation, mean ejection fraction was 14% ± 4%, 7 (54%) patients had previous cardiac surgery, 4 (31%) were on mechanical ventilation, and 3 (23%) patients were on dialysis. The mean duration of TAH support was 46 ± 40 days. Three (23%) patients died while on support after a mean of 15 days. Actuarial survival on support was 77% ± 12% at 30 days after implantation. Complications on support included stroke (n = 1, 8%), acute respiratory distress syndrome requiring prolonged intubation (n = 5, 38%) and acute renal failure requiring temporary dialysis (n = 5, 38%). Ten (77%) patients survived to be transplanted after a mean of 52 ± 42 days of support. Actuarial survival rates after transplant were 67% ± 16% at 1 month and 56% ± 17% at 1 year after transplantation. Conclusion:The TAH provides an alternative with low incidence of neurologic events in extremely fragile and complex patients waiting for heart transplantation. Complex and unusual anatomic conditions explained the current use of TAH.

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“…They do not specifically focus on mortality in the intensive care unit, which is especially dependent on preoperative clinical status. Klotz et al implemented a pre-operative risk score to predict mortality in the intensive care unit after VAD implantation by using easily obtained and quickly accessible clinical parameters (Klotz et al, 2010). By focusing on mortality in the intensive care unit, they tried to evaluate preoperative patients who were too sick for mechanical support and may not have survived their stay in the ICU.…”

Section: Ventricular Assist Devices 74mentioning

confidence: 99%