pre-operative serum potassium levels and peri-operative outcomes in patients undergoing cardiac surgery

Sanjay, O. P.

doi:10.1007/bf02872387

Cited by 11 publications

(10 citation statements)

References 17 publications

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“…Campbell et al [37] investigated the impact of maintaining serum potassium ≥ 3.6 mmol/L in comparison to ≥4.5 mmol/L on the incidence of NOAF after coronary artery bypass grafting, but the authors did not publish the results. In another study [36], preoperative hypokalemia (<3.5 mmol/L) was associated with AF. None of the abovementioned data concerned patients with AMI.…”

Section: Clinical Laboratory and Echocardiographic Parametersmentioning

confidence: 90%

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Comprehensive Use of Routine Clinical Parameters to Identify Patients at Risk of New-Onset Atrial Fibrillation in Acute Myocardial Infarction

Raczkowska-Golanko

Raczak

Gruchała

et al. 2021

JCM

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(1) Background: New-onset atrial fibrillation (NOAF) is a significant complication of acute myocardial infarction (AMI). Our study aimed to investigate whether routinely checked clinical parameters aid in NOAF identification in modernly treated AMI patients. (2) Patients and methods: Patients admitted consecutively within 2017 and 2018 to the University Clinical Centre in Gdańsk (Poland) with AMI diagnosis (necrosis evidence in a clinical setting consistent with acute myocardial ischemia) were enrolled. Medical history and clinical parameters were checked during NOAF prediction. (3) Results: NOAF was diagnosed in 106 (11%) of 954 patients and was significantly associated with in-hospital mortality (OR 4.54, 95% CI 2.50–8.33, p < 0.001). Age, B-type natriuretic peptide (BNP), C-reactive protein (CRP), high-sensitivity troponin I, total cholesterol, low-density lipoprotein cholesterol, potassium, hemoglobin, leucocytes, neutrophil/lymphocyte ratio, left atrium size, and left ventricular ejection fraction (LVEF) were associated with NOAF in the univariate logistic analysis, whereas age ≥ 66 yo, BNP ≥ 340 pg/mL, CRP ≥ 7.7 mg/L, and LVEF ≤ 44% were associated with NOAF in the multivariate analysis. (4) Conclusions: NOAF is a multifactorial, significant complication of AMI, leading to a worse prognosis. Simple, routinely checked clinical parameters could be helpful indices of this arrhythmia in current invasively treated patients with AMI.

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Section: Clinical Laboratory and Echocardiographic Parametersmentioning

confidence: 90%

“…One of the well-known parameters connected to AF development in the general population is low potassium level in serum [35][36][37][38]. In the Rotterdam Study [35], potassium below 3.50 mmol/L was associated with a higher risk of this arrhythmia.…”

Section: Clinical Laboratory and Echocardiographic Parametersmentioning

confidence: 99%

Comprehensive Use of Routine Clinical Parameters to Identify Patients at Risk of New-Onset Atrial Fibrillation in Acute Myocardial Infarction

Raczkowska-Golanko

Raczak

Gruchała

et al. 2021

JCM

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“…Goyal et al reported that serum potassium values of less than 3.5 or more than 5.0 mEq/L were associated with a high adverse cardiac event and mortality rate in patients with acute myocardial infarction [17]. Hypokalemia was also found to be a predictor of serious peri- and postoperative arrhythmias [18]. As shown in Figures 1A and 2 A, an increase in the number of repeat critical value s for serum potassium was closely related to an increase in mortality (from 4.5% to 9.9% and 10.2%) with a decrease in healing rating (from 17.7% to 10.7% and 7.7%).…”

Section: Discussionmentioning

confidence: 99%

Analysis of Laboratory Repeat Critical Values at a Large Tertiary Teaching Hospital in China

2013

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ContextAs a patient safety measure, laboratories are required to have a critical values policy by regulatory agencies. Unfortunately, little information is available on repeat critical values for the same analyte(s) on the same patient.ObjectiveTo investigate the occurrence and distribution of repeat critical values and the relationship between the frequency of such values and patient outcome to provide information for hospitals on improving reporting policies.MethodsEleven laboratory critical value lists, including chemistry and hematology analytes, were selected from a tertiary hospital in China in the year 2010. The distribution and interval time for each repeat critical value were calculated. Serum potassium and platelet count were used as examples to illustrate the relationship between the frequency of the repeat critical values and patient outcome.ResultsAll test items on the critical value list were prone to the occurrence of repeat critical values. On average, each patient who experienced critical values had 2.10 occurrences. The median interval time for each repeat critical value varied, with most being longer than 8 hours. For those patients who had repeat critical values of serum potassium and platelet count, along with the increased frequency, the patients had a longer hospital stay and a generally worse outcome.ConclusionsPatient can have a number of repeat critical values and the frequency of these values is closely related to patient outcome. A careful evaluation is warranted if a laboratory chooses to adopt a policy of not reporting each repeat critical value.

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“…NOAF and AF groups had the highest WBC on admission, and the NOAF group had a peak WBC during the second day of in-hospital treatment ( Table 3 , Figure 3 ). Low serum potassium level is the next well-known characteristic linked to the development of AF in the general population [ 23 , 32 , 33 , 34 ]. In our previous study, potassium levels below 4.2 mmol/L were found to be crucial in revealing the NOAF probability [ 9 ].…”

Section: Discussionmentioning

confidence: 99%

New-Onset Atrial Fibrillation in Acute Myocardial Infarction Is a Different Phenomenon than Other Pre-Existing Types of That Arrhythmia

Raczkowska-Golanko

Młodziński

Raczak

et al. 2022

JCM

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(1) Background: Atrial fibrillation (AF) in acute myocardial infarction (AMI) could worsen the prognosis. Yet, there is no definitive answer to whether new-onset AF (NOAF) is a more aggravating diagnosis than other types of that arrhythmia. The purpose of our study was to compare in-hospital clinical course and outcomes of NOAF patients contrary to patients with other pre-existing types of AF. (2) Methods: AMI patients hospitalized in the high-volume cardiological center within 2017–2018 were included in the study. NOAF was noticed in 106 (11%) patients, 95 (10%) with an AF history and AF during AMI formed the AF group, 60 (6%) with an AF history but without AF during AMI constituted the Prior-AF group, and 693 (73%) patients were without an AF before and during AMI. Medical history, routinely monitored clinical parameters, and in-hospital outcomes were analyzed between the groups. (3) Results: NOAF patients, contrary to others, initially had the highest high-sensitivity troponin I (hsTnI), B-type natriuretic peptide (BNP), C-reactive protein (CRP), and glucose levels, and the lowest potassium concentration, with the worst profile of changes for that parameter within the first four days of hospitalization. NOAF patients had the highest rate of ST-elevated AMI (40%), the longest hospitalization (p < 0.001), and the highest in-hospital mortality (p < 0.001). Not NOAF, but other AF groups (AF and Prior-AF groups) were more burdened with the previous comorbidities. (4) Conclusions: NOAF could be a distinct phenomenon in AMI patients, identifying those with the worst clinical in-hospital course and outcomes as compared to other types of AF.

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pre-operative serum potassium levels and peri-operative outcomes in patients undergoing cardiac surgery

Cited by 11 publications

References 17 publications

Comprehensive Use of Routine Clinical Parameters to Identify Patients at Risk of New-Onset Atrial Fibrillation in Acute Myocardial Infarction

Comprehensive Use of Routine Clinical Parameters to Identify Patients at Risk of New-Onset Atrial Fibrillation in Acute Myocardial Infarction

Analysis of Laboratory Repeat Critical Values at a Large Tertiary Teaching Hospital in China

New-Onset Atrial Fibrillation in Acute Myocardial Infarction Is a Different Phenomenon than Other Pre-Existing Types of That Arrhythmia

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