This study presents a decision-support methodology to design and optimize modular Boost converters in the context of fuel-cell electric vehicles. It involves the utilization of interleaved techniques to reduce fuel-cell current ripple, enhance system efficiency, tackle issues related to weight and size concerns, and offer better flexibility and modularity within the converter. The methodology incorporates emerging technologies by wide-bandgap semiconductors, providing better efficiency and higher temperature tolerance. It employs a multiphysical approach, considering electrical, thermal, and efficiency constraints to achieve an optimal power architecture for FCHEVs. Results demonstrate the advantages of wide-bandgap semiconductor utilization in terms of volume reduction and efficiency enhancements for different power levels. Results from one of the considered power levels highlight the feasibility of certain architectures through the utilization of WBG devices. These architectures reveal improvements in both efficiency and volume reduction as a result of incorporating WBG devices. Additionally, the analysis presents a comparison of manufacturing cost between standard and wide-bandgap semiconductors to demonstrate the market penetration potential.