The present burial depth of the paleokarst reservoirs in the Tarim Basin is greater than 5000m, which premises rigorous demands for the data quality for accurate predictions. Although routinely used for reservoir prediction, the conventional full-stack data are often contaminated by the AVO (amplitude versus offset) effects no matter how much signal to noise ratio degree can be enhanced via stacking. This contamination usually changes with different geological deposits, and could reach an inappropriate and unacceptable level for the deeply buried carbonate reservoir in the Tarim Basin. In this paper, the pure P-wave data theoretically inverted through AVO effects removal are employed to improve reservoir prediction, which are illustrated by the comparisons with that of the conventional full-stack data for the classical four AVO models and the field data in the ZG8 area, Tazhong Uplift, central Tarim Basin. The dominant frequency has been improved for 8 Hz from 15 to 23 Hz in the target Yingshan formation, Ordovician through AVO effects removal, and the reflection events of the pure P-wave data are obviously more continuous comparing with that of the full-stack data. The fake potential reservoir caused by AVO effects in the northeast area has been removed, while the integral delineation of paleokarst reservoirs have been significantly improved with a higher fitness with the oil-testing results, which are more beneficial for later on exploration. The pure P-wave data inversion is in essence an important complement to current processing strategy.